How to Pick the Right HMO Supplements? - by Layer Origin

Layer Origin Product Guide - 2024

 

Product

Key Benefits

Form and Key Ingredients

Who Is It For?

Akkermansia muciniphila Daily Probiotic with PureHMO Prebiotic

Akkermansia

Probiotic bacteria linked to weight management, healthy gut function, metabolism, blood sugar control, and strengthening of the gut barrier. 

HMO prebiotics support the innate immune system by blocking pathogens. 

Reduces inflammation by lowering the activity of pro-inflammatory cytokines.

Supports the production of healthy gut bacteria like Akkermansia muciniphila and others and boosts beneficial metabolites like butyrate.

Capsules


100 million CFUs of Akkermansia muciniphila probiotic bacteria 


250 mg of 2’Fucosyllactose (2’FL) HMO prebiotics 


750 mg of non-GMO resistant starch 



People with leaky gut or gut dysbiosis.

 

People looking to support weight management, metabolism, or blood sugar control. 


People with IBS or digestive symptoms, like gas, bloating, or constipation. 



Organic Apple Peel Powder

Apple peel

 

Antioxidants fight inflammation and support gut, heart, and joint health. 


Provides soluble and insoluble fiber.


Feeds healthy bacteria like Akkermansia, a probiotic linked to weight control, healthy guts, and blood sugar control. 

Powder


4.2 grams of AppleActiv apple peel powder per serving

People with constipation, dysbiosis, oxidative stress, or inflammation.



PureHMO® Human Milk Oligosaccharide (HMO 2'FL) Super Prebiotic Powder

Supports the growth of 200 billion healthy gut bacteria per serving, which can strengthen the intestinal lining to reduce leaky gut and its symptoms.


Supports brain development, neuronal transmission, and cognitive function. 


Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.

Powder


Contains 1,950 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL)

People with leaky gut or gut dysbiosis. 


People with IBS or digestive symptoms, like gas, bloating, or constipation. 



PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules

Supports the growth of 180 billion healthy gut bacteria per serving, which can strengthen the intestinal lining to reduce leaky gut and its symptoms.


Supports the innate immune system by blocking pathogens and reducing inflammation. 


Supports brain development, neuronal transmission, and cognitive function.


Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.

Capsules


1,800 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL)

People with leaky gut or gut dysbiosis. 


People with IBS or digestive symptoms, like gas, bloating, or constipation. 



SuperHMO® Human Milk Oligosaccharide Synbiotic: Prebiotic + Probiotic Combo

Feed key probiotic species in your gut like Bifidobacterium and Akkermansia, helping to strengthen the intestinal barrier and support gut microbiome diversity. 



10 probiotic strains work synergistically to help with immune function, digestive health, and mental health. 

Capsules


5 Kinds of HMO prebiotics and 10 probiotic strains totaling 40 billion CFUs (10 billion CFU/serving of Bifidobacteria strains, and 30 billion CFU/serving of Lactobacillus strains). 

People with IBS, constipation, or gut dysbiosis. 



PureHMO® IBS Support with IBS Defend Probiotic

IBS support

 

Improves IBS symptoms like constipation, gas, bloating, and diarrhea.


Combines Lactobacillus acidophilus probiotics with HMO prebiotic (2'-FL and LNnT) to restore beneficial microflora in the gut. 


Restores the gut lining, strengthens gut barriers, builds gut bacteria balance, and defends against bad bacteria and food intolerance. 

Powder


10 billion CFU of Lactobacillus acidophilus bacteria


1,000 mg of Lacto-n-neotetraose (LNnT), a type of HMO prebiotic


4,000 mg of  2’Fucosyllactose (2’FL), a type of HMO prebiotic. 

People with IBS.

PureHMO® Tri-Prebiotic for Constipation - HMO, GOS, Inulin FOS

Relieves constipation and improves bowel regularity.


Feed different strains of probiotics in the gut (more than 50 strains) and help to increase the diversity of gut microbiota.


A greater gut microbiome diversity can digest food more efficiently, reducing bloating, inflammation, and constipation symptoms. 

Powder form


1,000 mg of HMO (2’FL)

1,000 mg of GOS

2,000 mg of inulin (FOS)



People with IBS-C or constipation.



Simple Reds - Organic Red Polyphenols Fruit Powder

red fruits powder

 

Fights inflammation and oxidative stress.


Helps support the growth of healthy gut bacteria like Bifidobacteria and Akkermansia

Powdered form


Organic Strawberry Powder, Organic Cranberry Powder, Organic Apple Peel Powder, Organic Goji Berry Powder, and Organic Beet Root Powder



People who want an antioxidant-loaded powder to fight inflammation and oxidative stress.

People who want an energy boost. 



SuperHMO® Prebiotic for Kids - 5 HMOs

Mimics the composition of the true HMO profile found in breast milk.


Supports brain development, neuronal transmission, and cognitive function.


Support kids’ immune, brain, and digestive health. 

Powdered form 

540 mg of 2’FL HMO

150 mg of LNT

140 mg of LNnT

120 mg of 6’SL

50 mg of 3’SL 

Kids looking to improve digestive health, cognitive function, or immune health.



SuperHMO® Prebiotic Mix with 5 HMOs

SuperHMO

 

Promotes the growth of more than 100 strains of beneficial bacteria in the gut through cross-feeding reactions.


Supports brain development, neuronal transmission, and cognitive function.


Supports immune, brain, and digestive health. 

Powder form 

2,250 mg of 2’FL

650 mg of LNT

600 mg of LNnT

500 mg of 6’SL

200 mg of 3’SL



Anyone looking to support digestive, immune, or cognitive health. 



 

Akkermansia muciniphila Daily Probiotic with PureHMO Prebiotic

The Akkermansia muciniphila Daily Probiotic with PureHMO Prebiotic is a premium synbiotic gut health formula that combines the healthy probiotic bacteria Akkermansia muciniphila with 2’FL HMO prebiotics. 

Key Benefits: 

  • Akkermansia muciniphila is a potent probiotic bacteria linked to weight management, healthy gut function, metabolism and blood sugar control, and strengthening of the gut barrier. 
  • HMO prebiotics support the innate immune system by blocking pathogens. They also reduce inflammation by lowering the activity of pro-inflammatory cytokines.
  • The prebiotics (2’FL and resistant starch) further support the production of healthy gut bacteria like Akkermansia muciniphila and boost beneficial metabolites like butyrate.
  • Metabolites from the HMO prebiotic 2’FL also support brain development, neuronal transmission, and cognitive function.

Who Is It For?

  • People with leaky gut or gut dysbiosis. 
  • People looking to support weight management, metabolic function, and blood sugar control. 
  • People with IBS or digestive symptoms, like gas, bloating, or constipation. 
  • You can use Akkermansia muciniphila Daily Probiotic with PureHMO Prebiotic in combination with other Pure HMO Prebiotics to further boost the growth of Akkermansia and other healthy gut bacteria. 

Form and Key Ingredients:

  • Capsule form
  • Probiotics: 100 million CFUs of Akkermansia muciniphila bacteria 
  • Prebiotics: 250 mg of 2’Fucosyllactose (2’FL) and 750 mg of non-GMO resistant starch 

Organic Apple Peel Powder

The Organic Apple Peel Powder is an antioxidant-loaded and nutrient-rich powder made solely from organic apple peels. 

Key Benefits of Apple Peel Powder:

  • Rich in the antioxidant quercetin, which fights inflammation and supports gut, heart, and joint health. 
  • Feeds healthy bacteria like Akkermansia muciniphila, which is a probiotic linked to weight control, healthy guts, and blood sugar control. 
  • Provides soluble and insoluble fiber, which are beneficial for constipation and dysbiosis, as fiber increases the growth of the healthy bacteria Bifidobacteria. 
  • Contains micronutrients and phytonutrients, including vitamin C, vitamin A, potassium, calcium, folate, iron, and ursolic acid—an antioxidant that may reduce inflammation, help with blood sugar regulation, and reduce body fat.

Who Should Use Apple Peel Powder?

  • People with constipation, dysbiosis, oxidative stress, or inflammation.
  • The Apple Peel Powder can be used in combination with HMO supplements, such as the PureHMO® prebiotic or PureHMO® Tri-Prebiotic for a gut reset protocol. 

Form and Key Ingredients: 

  • Powder form
  • Contains 4.2 grams of AppleActiv apple peel powder per serving, which is equivalent to the peels from 2 medium apples or 3 small apples.

PureHMO® Human Milk Oligosaccharide (HMO 2'FL) Super Prebiotic Powder

The PureHMO® Human Milk Oligosaccharide (HMO 2'FL) Super Prebiotic Powder is an HMO powder—a prebiotic naturally found in breast milk—that feeds healthy gut bacteria and strengthens the gut lining. 

Key Benefits:

  • Supports the growth of 200 billion healthy gut bacteria per serving, including probiotics like Bifidobacterium and Akkermansia muciniphila, which strengthen the intestinal lining to reduce leaky gut and its symptoms. 
  • HMO prebiotics support the innate immune system by blocking pathogens and reducing inflammation. 
  • Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
  • Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.

Who Is It For?

  • People with leaky gut or gut dysbiosis. 
  • People with IBS or digestive symptoms, like gas, bloating, or constipation. 

Form and Key Ingredients:

  • Powder form
  • Contains 1,950 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL).
  • This product contains trace amounts of lactose, but it is considered safe for people with lactose intolerance when taken at the recommended dosage of approximately 2 grams.

PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules

PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules is a capsule version of HMO—a prebiotic naturally found in breast milk—that feeds healthy gut bacteria and strengthens the gut lining. 

Key Benefits:

  • Supports the growth of 180 billion healthy gut bacteria per serving, including probiotics like Bifidobacterium, which strengthen the intestinal lining to reduce leaky gut and its symptoms. 
  • HMO prebiotics support the innate immune system by blocking pathogens and reducing inflammation. 
  • Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
  • Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.

Who Is It For?

  • People with leaky gut or gut dysbiosis. 
  • People with IBS or digestive symptoms, like gas, bloating, or constipation. 

Form and Key Ingredients:

  • Capsule form
  • 1,800 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL)
  • Also contains organic pea protein and a vegetable capsule. 
  • This product contains trace amounts of lactose, but it is considered safe for people with lactose intolerance when taken at the recommended dosage of approximately 2 grams.

SuperHMO® Human Milk Oligosaccharide Synbiotic: Prebiotic + Probiotic Combo

The SuperHMO® Human Milk Oligosaccharide Synbiotic: Prebiotic + Probiotic Combo is a synbiotic, which combines prebiotic HMO and probiotics that work synergistically to support gut and immune health. 

Key Benefits:

  • 5 Kinds of HMO prebiotics act as food for probiotic bacteria to survive and thrive, which improves gut health and reduces dysbiosis. 
  • 10 probiotic strains work synergistically to help with immune function, digestive health, and mental health. 
  • HMO prebiotics feed key probiotic species in the gut like Bifidobacterium and Akkermansia, helping to strengthen the intestinal barrier and support gut microbiome diversity. 

Who Is It For?

  • People with IBS, constipation, or gut dysbiosis. 
  • You can use this product in combination with PureHMO® super prebiotic powder, PureHMO® super prebiotic capsules, or PureHMO® Tri-Prebiotic.

Form and Key Ingredients:

  • Capsule form
  • 1,000 mg HMO prebiotics (2’FL)
  • 10 probiotic strains totaling 40 billion CFUs (10 billion CFU/serving of Bifidobacteria strains, and 30 billion CFU/serving of Lactobacillus strains). 
  • This product contains trace amounts of lactose, but it is considered safe for people with lactose intolerance when taken at the recommended dosage of approximately 2 grams.

PureHMO® IBS Support with IBS Defend Probiotic

The PureHMO® IBS Support with IBS Defend Probiotic combines probiotics with HMO prebiotics to help with IBS symptoms. 

Key Benefits:

  • Improves IBS symptoms like constipation, gas, bloating, and diarrhea.
  • Combines Lactobacillus acidophilus probiotics with HMO prebiotics (2'-FL and LNnT) to restore beneficial microflora in the gut. 
  • This combination can restore the gut lining, strengthen gut barriers, build gut bacteria balance, and defend against bad bacteria and food intolerance. 

Who Is It For?

  • People with IBS. 

Form and Key Ingredients:

  • Powder form
  • 10 billion CFU of Lactobacillus acidophilus bacteria
  • 1,000 mg of Lacto-n-neotetraose (LNnT), a type of HMO prebiotic 
  • 4,000 mg of  2’Fucosyllactose (2’FL), a type of HMO prebiotic

PureHMO® Tri-Prebiotic for Constipation - HMO, GOS, Inulin FOS

The PureHMO® Tri-Prebiotic for Constipation - HMO, GOS, Inulin FOS contains three types of prebiotics, making it great for constipation.

Key Benefits:

  • Over 4 grams of prebiotics per serving (2’FL HMO, galactooligosaccharides [GOS], and inulin fructooligosaccharide [FOS]) help with constipation. 
  • These three types of prebiotics feed different strains of probiotics in the gut (more than 50 strains) and help to increase the diversity of gut microbiota.
  • A greater gut microbiome diversity can digest food more efficiently, reducing bloating, inflammation, and constipation symptoms. 
  • 4000 mg of prebiotic fiber help to relieve constipation and improve bowel regularity.

Who Is It For?

  • People with IBS-C or constipation.

Form and Key Ingredients:

  • Powder form
  • 1,000 mg of HMO (2’FL)
  • 1,000 mg of GOS
  • 2,000 mg of inulin (FOS) 

Simple Reds - Organic Red Polyphenols Fruit Powder

The Simple Reds - Organic Red Polyphenols Fruit Powder contains a blend of five red fruit and vegetables that are high in polyphenols. 

Key Benefits:

  • Polyphenols in organic whole beetroot powder, organic whole cranberry powder, organic goji berry powder, organic whole strawberry powder, and organic apple peel powder fight inflammation and oxidative stress.
  • The plant polyphenols in this powder can help support the growth of healthy gut bacteria like Bifidobacteria and Akkermansia

Who Is It For?

  • People who want an antioxidant-loaded powder to fight inflammation and oxidative stress.
  • People who want an energy boost. 

Form and Key Ingredients:

  • Powder form
  • Organic Strawberry Powder, Organic Cranberry Powder, Organic Apple Peel Powder, Organic Goji Berry Powder, and Organic Beet Root Powder

SuperHMO® Prebiotic for Kids - 5 HMOs

SuperHMO® Prebiotic for Kids - 5 HMOs is a premium mix of prebiotics that can help feed the good bacteria in kids’ guts and support immune and brain health. 

Key Benefits:

  • Contains a patent-pending combination of 5 HMOs that mimic the composition of the true HMO profile found in breast milk (Fucosyllactose (2'-FL), Lacto-N-tetraose (LNT), Lacto-N-neotetraose (LNnT), 6'-Sialyllactose (6'SL), and 3'-Sialyllactose (3'SL). 
  • Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
  • This combination of HMOs can support kids’ immune, brain, and digestive health. 

Who Is It For?

  • Kids looking to improve digestive health, cognitive function, or immune health.

Form and Key Ingredients:

  • Powdered form 
  • 540 mg of 2’FL HMO
  • 150 mg of LNT
  • 140 mg of LNnT
  • 120 mg of 6’SL
  • 50 mg of 3’SL 

SuperHMO® Prebiotic Mix with 5 HMOs

SuperHMO® Prebiotic Mix with 5 HMOs is a patent-pending combination of HMOs that can help feed good gut bacteria and support immune and brain health. 

Key Benefits:

  • Contains a patent-pending combination of 5 HMOs that mimic the composition of the true HMO profile found in breast milk (Fucosyllactose (2'-FL), Lacto-N-tetraose (LNT), Lacto-N-neotetraose (LNnT), 6'-Sialyllactose (6'SL), and 3'-Sialyllactose (3'SL). 
  • These HMOs promote the growth of more than 100 strains of beneficial bacteria in the gut through cross-feeding reactions.
  • Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
  • This combination of HMOs can support immune, brain, and digestive health. 

Who Is It For?

  • Anyone looking to support digestive, immune, or cognitive health. 

Form and Key Ingredients:

  • Powder form 
  • 2,250 mg of 2’FL
  • 650 mg of LNT
  • 600 mg of LNnT
  • 500 mg of 6’SL
  • 200 mg of 3’SL