How to Pick the Right HMO Supplements? - by Layer Origin

Layer Origin Product Guide - 2024

Product	Key Benefits	Form and Key Ingredients	Who Is It For?
Akkermansia muciniphila Daily Probiotic with PureHMO Prebiotic	Probiotic bacteria linked to weight management, healthy gut function, metabolism, blood sugar control, and strengthening of the gut barrier.  HMO prebiotics support the innate immune system by blocking pathogens.  Reduces inflammation by lowering the activity of pro-inflammatory cytokines. Supports the production of healthy gut bacteria likeAkkermansia muciniphilaand others and boosts beneficial metabolites like butyrate.	Capsules 100 million CFUs ofAkkermansia muciniphilaprobiotic bacteria  250 mg of 2’Fucosyllactose (2’FL) HMO prebiotics  750 mg of non-GMO resistant starch	People with leaky gut or gut dysbiosis.   People looking to support weight management, metabolism, or blood sugar control.  People with IBS or digestive symptoms, like gas, bloating, or constipation.
Organic Apple Peel Powder	Antioxidants fight inflammation and support gut, heart, and joint health.  Provides soluble and insoluble fiber. Feeds healthy bacteria likeAkkermansia, a probiotic linked to weight control, healthy guts, and blood sugar control.	Powder 4.2 grams of AppleActiv apple peel powder per serving	People with constipation, dysbiosis, oxidative stress, or inflammation.
PureHMO® Human Milk Oligosaccharide (HMO 2'FL) Super Prebiotic Powder	Supports the growth of 200 billion healthy gut bacteria per serving, which can strengthen the intestinal lining to reduce leaky gut and its symptoms. Supports brain development, neuronal transmission, and cognitive function.  Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.	Powder Contains 1,950 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL)	People with leaky gut or gut dysbiosis.  People with IBS or digestive symptoms, like gas, bloating, or constipation.
PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules	Supports the growth of 180 billion healthy gut bacteria per serving, which can strengthen the intestinal lining to reduce leaky gut and its symptoms. Supports the innate immune system by blocking pathogens and reducing inflammation.  Supports brain development, neuronal transmission, and cognitive function. Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.	Capsules 1,800 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL)	People with leaky gut or gut dysbiosis.  People with IBS or digestive symptoms, like gas, bloating, or constipation.
SuperHMO® Human Milk Oligosaccharide Synbiotic: Prebiotic + Probiotic Combo	Feed key probiotic species in your gut likeBifidobacterium andAkkermansia, helping to strengthen the intestinal barrier and support gut microbiome diversity.  10 probiotic strains work synergistically to help with immune function, digestive health, and mental health.	Capsules 5 Kinds of HMO prebiotics and 10 probiotic strains totaling 40 billion CFUs (10 billion CFU/serving of Bifidobacteria strains, and 30 billion CFU/serving ofLactobacillus strains).	People with IBS, constipation, or gut dysbiosis.
PureHMO®IBS Support with IBS Defend Probiotic	Improves IBS symptoms like constipation, gas, bloating, and diarrhea. CombinesLactobacillus acidophilus probiotics with HMO prebiotic (2'-FL and LNnT) to restore beneficial microflora in the gut.  Restores the gut lining, strengthens gut barriers, builds gut bacteria balance, and defends against bad bacteria and food intolerance.	Powder 10 billion CFU ofLactobacillus acidophilus bacteria 1,000 mg of Lacto-n-neotetraose (LNnT), a type of HMO prebiotic 4,000 mg of  2’Fucosyllactose (2’FL), a type of HMO prebiotic.	People with IBS.
PureHMO® Tri-Prebiotic for Constipation - HMO, GOS, Inulin FOS	Relieves constipation and improves bowel regularity. Feed different strains of probiotics in the gut (more than 50 strains) and help to increase the diversity of gut microbiota. A greater gut microbiome diversity can digest food more efficiently, reducing bloating, inflammation, and constipation symptoms.	Powder form 1,000 mg of HMO (2’FL) 1,000 mg of GOS 2,000 mg of inulin (FOS)	People with IBS-C or constipation.
Simple Reds - Organic Red Polyphenols Fruit Powder	Fights inflammation and oxidative stress. Helps support the growth of healthy gut bacteria likeBifidobacteria andAkkermansia.	Powdered form Organic Strawberry Powder, Organic Cranberry Powder, Organic Apple Peel Powder, Organic Goji Berry Powder, and Organic Beet Root Powder	People who want an antioxidant-loaded powder to fight inflammation and oxidative stress. People who want an energy boost.
SuperHMO® Prebiotic for Kids - 5 HMOs	Mimics the composition of the true HMO profile found in breast milk. Supports brain development, neuronal transmission, and cognitive function. Support kids’ immune, brain, and digestive health.	Powdered form  540 mg of 2’FL HMO 150 mg of LNT 140 mg of LNnT 120 mg of 6’SL 50 mg of 3’SL	Kids looking to improve digestive health, cognitive function, or immune health.
SuperHMO® PrebioticMix with 5 HMOs	Promotes the growth of more than 100 strains of beneficial bacteria in the gut through cross-feeding reactions. Supports brain development, neuronal transmission, and cognitive function. Supports immune, brain, and digestive health.	Powder form  2,250 mg of 2’FL 650 mg of LNT 600 mg of LNnT 500 mg of 6’SL 200 mg of 3’SL	Anyone looking to support digestive, immune, or cognitive health.

Akkermansia muciniphila Daily Probiotic with PureHMO Prebiotic

TheAkkermansia muciniphila Daily Probiotic with PureHMO Prebiotic is a premium synbiotic gut health formula that combines the healthy probiotic bacteriaAkkermansia muciniphila with 2’FL HMO prebiotics. 

Key Benefits: 

• Akkermansia muciniphila is a potent probiotic bacteria linked to weight management, healthy gut function, metabolism and blood sugar control, and strengthening of the gut barrier. 
• HMO prebiotics support the innate immune system by blocking pathogens. They also reduce inflammation by lowering the activity of pro-inflammatory cytokines.
• The prebiotics (2’FL and resistant starch) further support the production of healthy gut bacteria likeAkkermansia muciniphilaand boost beneficial metabolites like butyrate.
• Metabolites from the HMO prebiotic 2’FL also support brain development, neuronal transmission, and cognitive function.

Who Is It For?

• People with leaky gut or gut dysbiosis. 
• People looking to support weight management, metabolic function, and blood sugar control. 
• People with IBS or digestive symptoms, like gas, bloating, or constipation. 
• You can useAkkermansia muciniphila Daily Probiotic with PureHMO Prebiotic in combination with other Pure HMO Prebiotics to further boost the growth ofAkkermansia and other healthy gut bacteria. 

Form and Key Ingredients:

• Capsule form
• Probiotics: 100 million CFUs ofAkkermansia muciniphilabacteria 
• Prebiotics: 250 mg of 2’Fucosyllactose (2’FL) and 750 mg of non-GMO resistant starch 

Organic Apple Peel Powder

TheOrganic Apple Peel Powder is an antioxidant-loaded and nutrient-rich powder made solely from organic apple peels. 

Key Benefits of Apple Peel Powder:

• Rich in the antioxidant quercetin, which fights inflammation and supports gut, heart, and joint health. 
• Feeds healthy bacteria likeAkkermansia muciniphila, which is a probiotic linked to weight control, healthy guts, and blood sugar control. 
• Provides soluble and insoluble fiber, which are beneficial for constipation and dysbiosis, as fiber increases the growth of the healthy bacteriaBifidobacteria. 
• Contains micronutrients and phytonutrients, including vitamin C, vitamin A, potassium, calcium, folate, iron, and ursolic acid—an antioxidant that may reduce inflammation, help with blood sugar regulation, and reduce body fat.

Who Should Use Apple Peel Powder?

• People with constipation, dysbiosis, oxidative stress, or inflammation.
• The Apple Peel Powder can be used in combination with HMO supplements, such as the PureHMO® prebiotic or PureHMO® Tri-Prebiotic for a gut reset protocol. 

Form and Key Ingredients: 

• Powder form
• Contains 4.2 grams of AppleActiv apple peel powder per serving, which is equivalent to the peels from 2 medium apples or 3 small apples.

PureHMO® Human Milk Oligosaccharide (HMO 2'FL) Super Prebiotic Powder

ThePureHMO® Human Milk Oligosaccharide (HMO 2'FL) Super Prebiotic Powder is an HMO powder—a prebiotic naturally found in breast milk—that feeds healthy gut bacteria and strengthens the gut lining. 

Key Benefits:

• Supports the growth of 200 billion healthy gut bacteria per serving, including probiotics likeBifidobacterium and Akkermansia muciniphila, which strengthen the intestinal lining to reduce leaky gut and its symptoms. 
• HMO prebiotics support the innate immune system by blocking pathogens and reducing inflammation. 
• Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
• Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.

Who Is It For?

• People with leaky gut or gut dysbiosis. 
• People with IBS or digestive symptoms, like gas, bloating, or constipation. 

Form and Key Ingredients:

• Powder form
• Contains 1,950 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL).
• This product contains trace amounts of lactose, but it is considered safe for people with lactose intolerance when taken at the recommended dosage of approximately 2 grams.

PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules

PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules is a capsule version of HMO—a prebiotic naturally found in breast milk—that feeds healthy gut bacteria and strengthens the gut lining. 

Key Benefits:

• Supports the growth of 180 billion healthy gut bacteria per serving, including probiotics likeBifidobacterium, which strengthen the intestinal lining to reduce leaky gut and its symptoms. 
• HMO prebiotics support the innate immune system by blocking pathogens and reducing inflammation. 
• Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
• Clinically proven to reduce key symptoms of IBS such as gas, bloating, constipation, and other digestive discomforts.

Who Is It For?

• People with leaky gut or gut dysbiosis. 
• People with IBS or digestive symptoms, like gas, bloating, or constipation. 

Form and Key Ingredients:

• Capsule form
• 1,800 mg of Human Milk Oligosaccharides (HMO) per serving, with 98% coming from 2’Fucosyllactose (2’FL)
• Also contains organic pea protein and a vegetable capsule. 
• This product contains trace amounts of lactose, but it is considered safe for people with lactose intolerance when taken at the recommended dosage of approximately 2 grams.

SuperHMO® Human Milk Oligosaccharide Synbiotic: Prebiotic + Probiotic Combo

TheSuperHMO® Human Milk Oligosaccharide Synbiotic: Prebiotic + Probiotic Combo is a synbiotic, which combines prebiotic HMO and probiotics that work synergistically to support gut and immune health. 

Key Benefits:

• 5 Kinds of HMO prebiotics act as food for probiotic bacteria to survive and thrive, which improves gut health and reduces dysbiosis. 
• 10 probiotic strains work synergistically to help with immune function, digestive health, and mental health. 
• HMO prebiotics feed key probiotic species in the gut likeBifidobacterium andAkkermansia, helping to strengthen the intestinal barrier and support gut microbiome diversity. 

Who Is It For?

• People with IBS, constipation, or gut dysbiosis. 
• You can use this product in combination with PureHMO® super prebiotic powder, PureHMO® super prebiotic capsules, or PureHMO® Tri-Prebiotic.

Form and Key Ingredients:

• Capsule form
• 1,000 mg HMO prebiotics (2’FL)
• 10 probiotic strains totaling 40 billion CFUs (10 billion CFU/serving ofBifidobacteria strains, and 30 billion CFU/serving ofLactobacillus strains). 
• This product contains trace amounts of lactose, but it is considered safe for people with lactose intolerance when taken at the recommended dosage of approximately 2 grams.

PureHMO® IBS Support with IBS Defend Probiotic

ThePureHMO® IBS Support with IBS Defend Probiotic combines probiotics with HMO prebiotics to help with IBS symptoms. 

Key Benefits:

• Improves IBS symptoms like constipation, gas, bloating, and diarrhea.
• CombinesLactobacillus acidophilus probiotics with HMO prebiotics (2'-FL and LNnT) to restore beneficial microflora in the gut. 
• This combination can restore the gut lining, strengthen gut barriers, build gut bacteria balance, and defend against bad bacteria and food intolerance. 

Who Is It For?

• People with IBS. 

Form and Key Ingredients:

• Powder form
• 10 billion CFU ofLactobacillus acidophilus bacteria
• 1,000 mg of Lacto-n-neotetraose (LNnT), a type of HMO prebiotic 
• 4,000 mg of  2’Fucosyllactose (2’FL), a type of HMO prebiotic

PureHMO® Tri-Prebiotic for Constipation - HMO, GOS, Inulin FOS

ThePureHMO® Tri-Prebiotic for Constipation - HMO, GOS, Inulin FOS contains three types of prebiotics, making it great for constipation.

Key Benefits:

• Over 4 grams of prebiotics per serving (2’FL HMO, galactooligosaccharides [GOS], and inulin fructooligosaccharide [FOS]) help with constipation. 
• These three types of prebiotics feed different strains of probiotics in the gut (more than 50 strains) and help to increase the diversity of gut microbiota.
• A greater gut microbiome diversity can digest food more efficiently, reducing bloating, inflammation, and constipation symptoms. 
• 4000 mg of prebiotic fiber help to relieve constipation and improve bowel regularity.

Who Is It For?

• People with IBS-C or constipation.

Form and Key Ingredients:

• Powder form
• 1,000 mg of HMO (2’FL)
• 1,000 mg of GOS
• 2,000 mg of inulin (FOS) 

Simple Reds - Organic Red Polyphenols Fruit Powder

TheSimple Reds - Organic Red Polyphenols Fruit Powder contains a blend of five red fruit and vegetables that are high in polyphenols. 

Key Benefits:

• Polyphenols in organic whole beetroot powder, organic whole cranberry powder, organic goji berry powder, organic whole strawberry powder, and organic apple peel powder fight inflammation and oxidative stress.
• The plant polyphenols in this powder can help support the growth of healthy gut bacteria likeBifidobacteria andAkkermansia. 

Who Is It For?

• People who want an antioxidant-loaded powder to fight inflammation and oxidative stress.
• People who want an energy boost. 

Form and Key Ingredients:

• Powder form
• Organic Strawberry Powder, Organic Cranberry Powder, Organic Apple Peel Powder, Organic Goji Berry Powder, and Organic Beet Root Powder

SuperHMO® Prebiotic for Kids - 5 HMOs

SuperHMO® Prebiotic for Kids - 5 HMOs is a premium mix of prebiotics that can help feed the good bacteria in kids’ guts and support immune and brain health. 

Key Benefits:

• Contains a patent-pending combination of 5 HMOs that mimic the composition of the true HMO profile found in breast milk (Fucosyllactose (2'-FL), Lacto-N-tetraose (LNT), Lacto-N-neotetraose (LNnT), 6'-Sialyllactose (6'SL), and 3'-Sialyllactose (3'SL). 
• Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
• This combination of HMOs can support kids’ immune, brain, and digestive health. 

Who Is It For?

• Kids looking to improve digestive health, cognitive function, or immune health.

Form and Key Ingredients:

• Powdered form 
• 540 mg of 2’FL HMO
• 150 mg of LNT
• 140 mg of LNnT
• 120 mg of 6’SL
• 50 mg of 3’SL 

SuperHMO® Prebiotic Mix with 5 HMOs

SuperHMO® Prebiotic Mix with 5 HMOs is a patent-pending combination of HMOs that can help feed good gut bacteria and support immune and brain health. 

Key Benefits:

• Contains a patent-pending combination of 5 HMOs that mimic the composition of the true HMO profile found in breast milk (Fucosyllactose (2'-FL), Lacto-N-tetraose (LNT), Lacto-N-neotetraose (LNnT), 6'-Sialyllactose (6'SL), and 3'-Sialyllactose (3'SL). 
• These HMOs promote the growth of more than 100 strains of beneficial bacteria in the gut through cross-feeding reactions.
• Metabolites from the HMO prebiotic 2’FL support brain development, neuronal transmission, and cognitive function.
• This combination of HMOs can support immune, brain, and digestive health. 

Who Is It For?

• Anyone looking to support digestive, immune, or cognitive health. 

Form and Key Ingredients:

• Powder form 
• 2,250 mg of 2’FL
• 650 mg of LNT
• 600 mg of LNnT
• 500 mg of 6’SL
• 200 mg of 3’SL