PureHMO® Human Milk Oligosaccharide Synbiotic: Prebiotic + Probiotic Combo

  • HMO Prebiotic + 40 billion Probiotics: Most probiotic supplements contain little or no prebiotics, which means there is not enough food for the probiotic bacteria. In comparison, our formula contains potent Pure HMO prebiotic (2'FL) and 40 billion CFU probiotics.
  • 10 Clinically Validated Strains: These strains work synergistically to help with your immune system, IBS & constipation, SIBO, healthy weight, and improve mental & overall health.
  • HMO Prebiotic: Human milk oligosaccharides help infants build a healthy digestive and immune system from scratch. There is no better prebiotic than HMO to promote the growth of beneficial bacteria and help you regain gut balance.


Restore Gut Microflora

Your gut microflora can be easily disrupted by stress, poor diet, antibiotic use, and more; take PureHMO Synbiotic (Pre+Pro) and ensure your gut has the right seeds and foundation to start with.

Boost Key Gut Species

Probiotics need prebiotic to survive and thrive. HMO prebiotics feed key probiotic species in your gut, such as Bifidobacterium and other beneficial bacteria, helping them repopulate and remain.

Promote Gut Diversity

Bifidobacterium bifidum, Bifidobacterium lactis, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus gasseri, Lactobacillus paracasei, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus

Stronger Gut Functions

HMO prebiotics also nourish Akkermansia, a key probiotic bacteria that helps strengthen your gut barriers and keeps toxins out of your body.

Backed Up By

Scientific Studies on HMO Prebiotic and Probiotic

expert opinion review stars

Generate Beneficial Metabolites - Short Chain Fatty Acids

"2’-FL is the most abundant HMO in many mothers and selectively promotes the growth of bifidobacterial strains. They are protective by lowering inflammation, enhancing gut barrier function and providing fuel for intestinal cells via generating short chain fatty acids"

Nutrition Insight (Top Nutrition Website)

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HMOs and Bacteria Work Independently & Coordinately

"HMOs and bacteria in human milk may function independently and coordinately to influence both maternal and infant health"

Prebiotics and Probiotics in Human Milk, 2016 (Book)

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Synergistic Effect

"Synbiotics are a combination of prebiotics and probiotics that are believed to have a synergistic effect by inhibiting the growth of pathogenic bacteria and enhancing the growth of beneficial organisms"

Integrative Medicine, 2022 (Book)

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Selectively Promote Bifido Species

"HMOs are not digested but are selectively utilized by certain beneficial gut bacteria, such as B. infantis and Bifidobacterium bifidum. HMOs can hinder the adhesion of pathogens to gut epithelial cells, directly affect the maturation and development of gut epithelial cells, and support immune functions"

Critical Reviews in Food Science and Nutrition, 2019 (Scientific Journal)

HMOs Have Been Featured In:

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Bifidobacteria: 10 Billion CFU/Serving
Lactobacillus: 30 Billion CFU/Serving
Total Probiotics: 40 Billion CFU/Serving

No, it is shelf-stable at room temperature. However, you can choose to keep it in your refrigerator for a longer shelf-life.

No, it is recommended to not take the PureHMO Synbiotic with hot beverages as the heat can kill the probiotics. However, you can add the PureHMO Synbiotic to coffee or tea when they are cooled to less than 42 oC.

Customer Reviews

Based on 33 reviews
Great products!

Great products! I no longer have food cravings or bloating. Will continue to use. Thanks.

Bye bye bloating

I got this product for my wife to address her bloating and gas issues. When taking this product, she has must less bloating days.

Kathy B.
Trust your gut- it will thank you

It's a great part of my daily routine.

good supplement and company

I believe this product improved my gut health

Carmen Kastner
Thanks layer origin!

I love this product! I have severe food sensitives. With taking this formula, it's helping with my food sensitivities and IBS. I don't go a day without it!