PureHMO® Human Milk Oligosaccharide Synbiotic

  • Prebiotic + Probiotic Combo: most other probiotic supplements contain just a small amount (<50 mg) of prebiotics. By comparison, our formula contains a potent 1000 mg of prebiotic (Human Milk Oligosaccharide) and 10 strains of probiotics, 40 Billion CFU. 
  • HMO Prebiotic: PureHMO® human milk oligosaccharide helps infants build a healthy digestive system from scratch. There is no better prebiotic than HMO to feed the probiotics and restore your gut.
  • Probiotic for Women and Men: PureHMO® Synbiotic is designed to restore the gut & immune system, relieve IBS & constipation, suppress SIBO, achieve healthy weight loss, and improve mental & overall health


Synbiotic: HMO Prebiotic + HMO Probiotics

Each serving provides 1000 mg of HMO and billions of bifidobacteria that feed on HMO

Regain Gut Balance

HMO feeds the bifidobacteria in your gut, where the metabolites of those bacteria feed other probiotic bacteria and restore gut balance

Promote Diversity of Gut Microbiome

10 strains of probiotics help promote the diversity of gut microbiota

Stronger Gut Functions

HMO super prebiotics feed Akkermansia and strengthen gut barriers

How It Works

expert opinion review stars

Nutrition Insight

"2’-FL is the most abundant HMO in many mothers and selectively promotes the growth of bifidobacterial strains, while generally known prebiotics promote bacterial growth on a broader level. Bifidobacteria are recognized as beneficial bacteria not only during infancy, but throughout human life. They are protective by lowering inflammation, enhancing gut barrier function and providing fuel for intestinal cells via generating short chain fatty acids"

expert opinion review stars

JOEL GREENE, Author, The Immunity Code

"What you're going to find with HMOs is that they are endemic to the formation of the immune system in the infant gut — and so HMOs have very, very strong presence informing immunity in the gut."

expert opinion review stars

Integrative Medicine, Book

"Synbiotics are a combination of prebiotics and probiotics that are believed to have a synergistic effect by inhibiting the growth of pathogenic bacteria and enhancing the growth of beneficial organisms"

expert opinion review stars

Critical Reviews in Food Science and Nutrition

"HMOs are not digested but are selectively utilized by certain beneficial gut bacteria, such as Bifidobacterium longum subsp. infantis (B. infantis) and Bifidobacterium bifidum. In addition to this prebiotic function, HMOs can hinder the adhesion of pathogens to gut epithelial cells, directly affect the maturation and development of gut epithelial cells, and support immune functions"

HMOs Have Been Featured In:

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Bifidobacteria: 10 Billion CFU/Serving
Lactobacillus: 30 Billion CFU/Serving
Total Probiotics: 40 Billion CFU/Serving

No, it is shelf-stable at room temperature. However, you can choose to keep it in your refrigerator for a longer shelf-life.

Yes, you can use it with PureHMO® super prebiotic powder, PureHMO® super prebiotic capsules, or PureHMO® Tri-Prebiotic.

Customer Reviews

Based on 12 reviews
Christo Cassassa
Keeps things moving!

I have been very happy with Pure HMO synbiotic. I am on medication that is extremely constipating and Pure HMO has been instrumental in helping my digestive system work properly. It has definitely been helpful with inflammation and my ability to move in the morning. In short, it's a wonderful addition to my health care regime for both mobility and motility. Thank you!

Brandi Nieding

So far I have noticed huge change in gut health. I highly recommend trying this product!!!!

Will Malcolm
Excellent probiotic + HMO stack

My wife and I have been using this product for a couple weeks now. We've both noticed better regularity, less gas and constipation, and overall healthier gut function!

Sherry Adams
Excellent Product

I can see why their products are all the rage

Dmitry Varenik
Not sure yet for certain...

Been having better bowel movements and better formed stools, my mother says it's been helping her too, and she doesn't take it consistently because she doesn't like taking pills, but also suffers from similar digestive issues as me after catching H.Pylori in the past like myself, also happy that this product passed the milk test which shows the probiotics are alive, as you can see in the picture, I had a strong feeling it would pass, since "Layer Origins" is affiliated with Cornell University, I hope you guys keep making more research and find a solution for people who have IBS and dysbiosis, thank you and have a great day...