PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules

PureHMO® super prebiotic is a high-purity human milk oligosaccharide with multiple health benefits, originally found in mother's milk. PureHMO® is produced by fermentation and purified to an unprecedented purity of 98%. This superior prebiotic offers more benefits than traditional oligosaccharides like GOS, FOS, and inulin due to its specific structure and unique functionality:

  • Promote Digestive Health: HMO prebiotic promotes the growth of probiotics like Bifidobacterium and Akkermansia Muciniphila, which supports a healthy gut environment.
  • Support Immune Functions: HMOs are more effective than non-human prebiotics in stimulating the innate immune system, blocking pathogens and viruses, and reducing inflammation.
  • Improve Cognitive Function: Unlike other prebiotic and probiotic products for adults, HMO metabolites promote brain development, neuronal transmission, and cognition.


      Super Prebiotic Fiber

      Feed Bifidobacteria and Akkermansia, increase beneficial bacteria in gut, build a healthy gut ecosystem.

      Cognitive Support

      HMO provide nutrients for brain development and cognitive functions

      Gut Comfort

      Clinically proven to reduce gas, bloating, constipation, and stomach pain, and other IBS symptoms

      Healthy Metabolism

      Boost the number of slim probiotics in the gut, which help with food digestion and improve metabolism

      How It Works

      Experts' Opinion On HMO

      expert opinion review stars


      "HMOs are helping to steer the gut towards immunity and steering the macrophages towards restoration of the gut lining — I actually know a lot of functional medicine doctors using this with their patients now."

      Host, The Ben greenfield fitness podcast

      expert opinion review stars


      "What you're going to find with HMOs is that they are endemic to the formation of the immune system in the infant gut — and so HMOs have very, very strong presence informing immunity in the gut."

      Author, The Immunity Code

      expert opinion review stars

      DR. RHONDA , Ph.D.

      "These beneficial bacteria (HMOS) produce short-chain fatty acids that prevent colonization of pathogenic bacteria in the gut. This bacteria (good bacteria promoted by HMOs) has been shown to set up the immune system."


      expert opinion review stars


      "They are food for the developing gut microbiome. They are prebiotics and they actually help the right bacteria, specifically bifidobacteria, to grow. And this also helps with development of the immune system."


      HMOs Have Been Featured In:

      fobes logo
      the new york times logo
      nature logo
      bloomberg logo


      No. Our HMO is technically something referred to as HiMO, which stands for Human identical Milk Oligosaccharide. It is produced via a complex fermentation and precise purification process and results in a powder that is molecularly identical to the HMO that is in human milk. All the benefits without any human milk involved.

      Yes. Research has shown that many people with lactose intolerance can tolerate up to 12 grams of lactose in one sitting, which is approximately the amount in one cup (230 ml) of milk. Layer Origin Nutrition recommends a total HMO serving size of 2.0 grams — therefore — even people with with lactose intolerance should be well below the limit of what they can tolerate, if they follow the recommended dosage.

      Believe it or not, it doesn't make a difference either way. This is because the HMO will not be digested the way that food would be digested. HMO makes its way undigested through your body down to the lower intestines, where it becomes the food for probiotic bacteria. So take HMO with food or without food. Either way is fine!

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      Our customer service team will answer it as soon as possible.

      Customer Reviews

      Based on 35 reviews
      Karen E
      Gut issues

      I’ve had gut issues for the longest time and this definitely is healing and other products that I use.

      Marilyn D Thuss
      Game changer!

      I have been using the PureHMO capsules for just about a month now. I like to take them with a really good plain greek yogurt that has active Bifidus probiotics in it. This is a very important bacteria for our gut, and the PureHMO is the favorite food of Bifidus bacteria. The first week, as I slowly added it to my diet, I didn’t really feel anything, except that I began to notice that I was not experiencing any bloating, which was common for me. I have not had any bloating at all since I have been using it. The second effect on my system is a surprising regularity in my bathroom habits. This has always been a problem for me, but now, shortly after I wake up in the morning, I have no problem going. This is huge for me, and a real game changer! I also bought the Pure HMO in the powder form, but found that it has a slight taste that I didn’t care for when mixed into my yogurt, so I just use that if I am having a smoothie.

      I am now also using the Layer Origin Apple peel powder which is another important food for the gut lining.

      Another game changer point is that these items are not probiotics, but rather probiotics, so I don’t have to worry about refrigeration or expiration dates. These items are food for the good bacteria in our gut, which is a much simpler approach and according to my readings, a much better approach. I love not having to worry about running out of my probiotics, nor the big expense of buying them. I feel really good digestion wise, and I have found the right solution for me. Great product! Thank you!

      Josie Flowers
      Giving my gut a fighting chance

      I learned about this product from Donna Shwenk. I trust her research. I’ve been taking this for about 3 weeks and am noticing a difference. I have severe diverticulosis and need help to heal my gut. Going to order the Apple peel powder too!

      Jamie Parker
      Great Prebiotic!

      During these times, you can never have enough Prebiotics! This one is great. Thanks!

      Helping to heal my leaky gut

      After years of digestive issues and MEBO I am noticing a difference in my gut health by switching from probiotics to prebiotics to repopulate my gut with good bacteria. I am ready to order a second bottle.