PureHMO® IBS Support with IBS Defend Probiotic

Notify me when this product is available:

  • Hits Root Cause of IBS: The imbalance of gut bacteria is one of the root causes of IBS. We focus on restoring the beneficial microflora and creating a positive environment for them to stay and thrive.  
  • Super Prebiotic HMOs: The unique blend of 2'-FL and  Lacto-n-neotetraose (LNnT) human milk oligosaccharides are clinically proven to relieve IBS symptoms, including constipation, gas, bloating, and diarrhea.
  • The IBS Defend Probiotic: The IBS defend Acidophilus probiotic strain was specially developed for IBS relief and was proven to reduce IBS discomfort in human trials.
  • Restore Gut Functions: The product is designed to restore the gut lining, strengthen gut barriers, build gut bacteria balance, and defend against bad bacteria and food intolerance. 


Restore Gut Microflora

Two kinds of HMOs: 2'-Fl and LNnT, to feed and restore bifidobacteria in the gut

Stool Consistency and Improved Regularity

Formulated with IBS Defend Lactobacillus acidophilus, a clinically-proven probiotic

Reduction of Abdominal Discomfort

Both HMOs and the probiotic were clinically proven to reduce abdominal discomfort (P<0.001, total~1000 participants)

Target the Root Cause of IBS

Gut microflora imbalance is one of the most important root causes of IBS. PureHMO® IBS Support is designed to restore gut flora and gut function.

Backed Up By

Scientific Studies on HMOs and IBS Defend Probiotic

expert opinion review stars

Improve Bowel Functions for IBS (317 patients)

"Daily oral administration of the 2 HMOs, 2'FL and LNnT in a 4:1 mix, for 12 weeks significantly improves bowel habits, other IBS symptoms, and health-related quality of life in adults who have clinical IBS diagnosis and fulfill the Rome IV criteria for IBS"

Clinical and Translational Gastroenterology, 2020 (Journal)

expert opinion review stars

Improve Abdominal Pain

"L. acidophilus and B. lactis UABla-12 improved abdominal pain and symptom severity scores with a corresponding normalization of bowel habits in adults with IBS." (Participants: 333 patients)

Nutrients, 2020 (Scientific Journal)

expert opinion review stars

Approved Functional Claims

"Health Canada authorizes functional claim that “Lactobacillus Acidophilus helps improve abdominal pain severity and symptomology in Irritable Bowel Syndrome in adolescents and adults”

Chr. Hansen / Health Canada

expert opinion review stars

Modulate Gut Microbiota

"Supplementation with 2′FL/LNnT modulated the gut microbiota, fecal and plasma metabolite profiles, but not the host mucosal response in IBS. Furthermore, the bifidogenic effect was associated with metabolite modulation. Overall, these findings support the assertion that 2′FL/LNnT supplementation modulate the intestinal microenvironment of patients with IBS, potentially related to health."

Nutrients, 2020 (Journal)

HMOs Have Been Featured In:

fobes logo
the new york times logo
nature logo
bloomberg logo


Gut microflora imbalance is one the most important root causes of IBS. Research indicates that the microflora in people with IBS differ from those in healthy people. Without good and balanced microflora, your digestive system will have difficulties fully digesting foods, which could trigger IBS.

The combination of two human milk oligosaccharides, 2'-FL and LNnT, feed good bacteria and enrich the biodiversity of gut microflora, especially those living on the gut lining. They are the key to normalizing the function of your gut.

You can simply mix the powder with water and take it right before meals. Please do not add the powder into hot beverages since this product also contains IBS Defend probiotic.

Menthol tends to solve the problem by suppressing bowel muscle spasms whereas PureHMO® IBS Support is designed to restore the gut flora and gut functions for a longterm fix.

Customer Reviews

Based on 39 reviews
PureHMO IBS support

My husband had chronic diarrhea ..tried different products. This one saved my husband and it works !! Nothing but a great product My husband took for week two scoops and healed that diarrhea! He will take everyday because this product works. This product game changer thank u for this product

Erin Kessler
Finally a Solution!

I have only started the IBS formula a few weeks ago and I already have started to feel better. There is no bad taste at all and it’s super easy to mix. I will definitely continue to take this product!

Quality of Life Has Returned

Layer Origin, I have been to many G.I. Doctors over the past 5 years since I discovered I’m dealing with IBS-C & and Leaky Gut. The blend of these 3 probiotics have given me my life back. I was having constant pain in multiple areas throughout my colon and stomach. I was unable to eat and had lost 20 pounds. This product has saved my life. Our gut creates 90% of our serotonin. I feel less depressed, sluggish, and have better cognitive responses. PLEASE never Stop making this LIFE CHANGING product. So many people go to gastroenterologists and receive no help. You are helping to change lives. Thank you so much.

Jose Carlos Marti
It is working

My leaky gut is improving. I feel more energetic and less bloated. It is working.

Leslie B.
Works for me.

Cleared up my diarrhea in two days. I've been having solid (but not hard) BMs for over a week now.