PureHMO® IBS Support with IBS Defend Probiotic

  • Hits Root Cause of IBS: The imbalance of gut bacteria is one of the root causes of IBS. We focus on restoring the beneficial microflora and creating a positive environment for them to stay and thrive.  
  • Super Prebiotic HMOs: The unique blend of 2'-FL and  Lacto-n-neotetraose (LNnT) human milk oligosaccharides are clinically proven to relieve IBS symptoms, including constipation, gas, bloating, and diarrhea.
  • The IBS Defend Probiotic: The IBS defend Acidophilus probiotic strain was specially developed for IBS relief and was proven to reduce IBS discomfort in human trials.
  • Restore Gut Functions: The product is designed to restore the gut lining, strengthen gut barriers, build gut bacteria balance, and defend against bad bacteria and food intolerance. 


Restore Gut Microflora

Two kinds of HMOs: 2'-Fl and LNnT, to feed and restore bifidobacteria in the gut

Stool Consistency and Improved Regularity

Formulated with IBS Defend Lactobacillus acidophilus, a clinically-proven probiotic

Reduction of Abdominal Discomfort

Both HMOs and the probiotic were clinically proven to reduce abdominal discomfort (P<0.001, total~1000 participants)

Target the Root Cause of IBS

Gut microflora imbalance is one of the most important root causes of IBS. PureHMO® IBS Support is designed to restore gut flora and gut function.

Backed Up By

Scientific Studies on HMOs and IBS Defend Probiotic

expert opinion review stars

Improve Bowel Functions for IBS (317 patients)

"Daily oral administration of the 2 HMOs, 2'FL and LNnT in a 4:1 mix, for 12 weeks significantly improves bowel habits, other IBS symptoms, and health-related quality of life in adults who have clinical IBS diagnosis and fulfill the Rome IV criteria for IBS"

Clinical and Translational Gastroenterology, 2020 (Journal)

expert opinion review stars

Improve Abdominal Pain

"L. acidophilus and B. lactis UABla-12 improved abdominal pain and symptom severity scores with a corresponding normalization of bowel habits in adults with IBS." (Participants: 333 patients)

Nutrients, 2020 (Scientific Journal)

expert opinion review stars

Approved Functional Claims

"Health Canada authorizes functional claim that “Lactobacillus Acidophilus helps improve abdominal pain severity and symptomology in Irritable Bowel Syndrome in adolescents and adults”

Chr. Hansen / Health Canada

expert opinion review stars

Modulate Gut Microbiota

"Supplementation with 2′FL/LNnT modulated the gut microbiota, fecal and plasma metabolite profiles, but not the host mucosal response in IBS. Furthermore, the bifidogenic effect was associated with metabolite modulation. Overall, these findings support the assertion that 2′FL/LNnT supplementation modulate the intestinal microenvironment of patients with IBS, potentially related to health."

Nutrients, 2020 (Journal)

HMOs Have Been Featured In:

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Gut microflora imbalance is one the most important root causes of IBS. Research indicates that the microflora in people with IBS differ from those in healthy people. Without good and balanced microflora, your digestive system will have difficulties fully digesting foods, which could trigger IBS.

The combination of two human milk oligosaccharides, 2'-FL and LNnT, feed good bacteria and enrich the biodiversity of gut microflora, especially those living on the gut lining. They are the key to normalizing the function of your gut.

You can simply mix the powder with water and take it right before meals. Please do not add the powder into hot beverages since this product also contains IBS Defend probiotic.

Menthol tends to solve the problem by suppressing bowel muscle spasms whereas PureHMO® IBS Support is designed to restore the gut flora and gut functions for a longterm fix.

Customer Reviews

Based on 30 reviews

Amazing against SIBO (Small Intestinal Bacterial Overgrowth)!

Sue Hahn
This worked great while I had IBS

Worked great while I had IBS

Tammy R
This product saved me!

I had 2 1/2 years of UC and This product helped me immediately. It's been almost a year and I have not had any symptoms. The microbiome is so important, especially as we age. I hope they never change this product!!! MY BODY LOVES IT!!!

Managing my colitis

This daily supplement is the only thing that has provided relief from colitis since I was diagnosed 15 years ago! Life changing.

Life Changing Product

Thank You so much for this product. I beg you never discontinue. Many people suffer with IBS. I began suffering about 3 years ago and had lost a huge quality of life. I could not eat without fear, and couldn’t leave the house with fear. This product has replaced an effective product from Culturelle that they discontinued. I didn’t know what to do. I found this product and it works better. I have energy all day, less anxiety, little to no intestinal pain, WAY less bloating, and I can finally sleep at night. Please never discontinue. Thank you for helping to provide people with IBS a better quality of life by addressing the root causes of IBS.