PureHMO® IBS Support with IBS Defend Probiotic

  • Hits Root Cause of IBS: The imbalance of gut bacteria is one of the root causes of IBS. We focus on restoring the beneficial microflora and creating a positive environment for them to stay and thrive.  
  • Super Prebiotic HMOs: The unique blend of 2'-FL and  Lacto-n-neotetraose (LNnT) human milk oligosaccharides are clinically proven to relieve IBS symptoms, including constipation, gas, bloating, and diarrhea.
  • The IBS Defend Probiotic: The IBS defend Acidophilus probiotic strain was specially developed for IBS relief and was proven to reduce IBS discomfort in human trials.
  • Restore Gut Functions: The product is designed to restore the gut lining, strengthen gut barriers, build gut bacteria balance, and defend against bad bacteria and food intolerance. 


Restore Gut Microflora

Two kinds of HMOs: 2'-Fl and LNnT, to feed and restore bifidobacteria in the gut

Stool Consistency and Improved Regularity

Formulated with IBS Defend Lactobacillus acidophilus, a clinically-proven probiotic

Reduction of Abdominal Discomfort

Both HMOs and the probiotic were clinically proven to reduce abdominal discomfort (P<0.001, total~1000 participants)

Target the Root Cause of IBS

Gut microflora imbalance is one of the most important root causes of IBS. PureHMO® IBS Support is designed to restore gut flora and gut function.

Backed Up By

Scientific Studies on HMOs and IBS Defend Probiotic

expert opinion review stars

Improve Bowel Functions for IBS (317 patients)

"Daily oral administration of the 2 HMOs, 2'FL and LNnT in a 4:1 mix, for 12 weeks significantly improves bowel habits, other IBS symptoms, and health-related quality of life in adults who have clinical IBS diagnosis and fulfill the Rome IV criteria for IBS"

Clinical and Translational Gastroenterology, 2020 (Journal)

expert opinion review stars

Improve Abdominal Pain

"L. acidophilus and B. lactis UABla-12 improved abdominal pain and symptom severity scores with a corresponding normalization of bowel habits in adults with IBS." (Participants: 333 patients)

Nutrients, 2020 (Scientific Journal)

expert opinion review stars

Approved Functional Claims

"Health Canada authorizes functional claim that “Lactobacillus Acidophilus helps improve abdominal pain severity and symptomology in Irritable Bowel Syndrome in adolescents and adults”

Chr. Hansen / Health Canada

expert opinion review stars

Modulate Gut Microbiota

"Supplementation with 2′FL/LNnT modulated the gut microbiota, fecal and plasma metabolite profiles, but not the host mucosal response in IBS. Furthermore, the bifidogenic effect was associated with metabolite modulation. Overall, these findings support the assertion that 2′FL/LNnT supplementation modulate the intestinal microenvironment of patients with IBS, potentially related to health."

Nutrients, 2020 (Journal)

HMOs Have Been Featured In:

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Gut microflora imbalance is one the most important root causes of IBS. Research indicates that the microflora in people with IBS differ from those in healthy people. Without good and balanced microflora, your digestive system will have difficulties fully digesting foods, which could trigger IBS.

The combination of two human milk oligosaccharides, 2'-FL and LNnT, feed good bacteria and enrich the biodiversity of gut microflora, especially those living on the gut lining. They are the key to normalizing the function of your gut.

You can simply mix the powder with water and take it right before meals. Please do not add the powder into hot beverages since this product also contains IBS Defend probiotic.

Menthol tends to solve the problem by suppressing bowel muscle spasms whereas PureHMO® IBS Support is designed to restore the gut flora and gut functions for a longterm fix.

Customer Reviews

Based on 23 reviews
Tracey Gehring
Thankful to Discover!

I was using another brand that, instead of just changing their packaging, they changed the whole formula that my gut did NOT like. After using for at least a year, and having excellent results with my IBS symptoms being much reduced, I was at a loss for what to do. Depressed at potentially going back to the “before times” with my IBS symptoms. I did some digging, searching the ingredients etc, and ran across the Layer Origin site and discovered this product. I am currently in my 2nd month using it and can report that so far so good. My “bad” IBS symptom days are becoming fewer and even less debilitating when they do arrive (less gut pain at least). I followed the recommendation on the container to ease into using, and I can say I had a couple days of gut disturbance (gas mostly), but that didn’t last too long and now all is fine. I will definitely be sticking with this product for the long haul! I only wish it was a little less costly, it’s about $15 more than the other stuff I was using and it’s only about 24 days worth vs the 30 days of the other brand. The cost is the only complaint I have about it - it’s been a great discovery otherwise for me!

Just what I was looking for!

After Culturelle "IBS Complete Support" changed their name and formula to "Abdominal Support & Comfort", it didn't work as well to control my IBS symptoms. Now that I'm on PureHMO IBS Support, however, my symptoms are practically gone again!! I couldn't be happier. Definitely recommend making the switch for anyone on the fence about it.

F. C.
Good for me

I have been taking this for a few weeks and feel like it’s helped with my IBS-C symptoms.

Jennifer L
Feel good

I feel like this product is helping calm down my digestive issues!

V Riley
PureHMO® IBS Support with DDS-01 Probiotic

Helped me lose a few pounds! What a wonderful surprise!