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      Layer Origin Blog for Gut Health and Gut Microbiome

      THE LAYER ORIGIN NUTRITION BLOG

      Hosted by Dr. Alexis Cowan From Princeton University
      Layer Origin Blog for Gut Health and Gut Microbiome

      How Do Human Milk Oligosaccharides (HMOs) Promote Brain Health?

      August 10, 2022 5 min read

      Three of the most studied HMOs are 2’FL, 3’SL, and 6’SL — let’s take a closer look at how these molecules impact our brain and what the research is telling us about HMOs and cognition.

      2’-FL is the most abundant HMO found in human milk and was the first HMO to be added to infant formula. The 2’FL is most strongly linked to immune health, brain development, and fighting inflammation. The ​​sialylated HMOs—3’SL and 6’SL—also are known to benefit brain health, as sialic acid is an essential nutrient to form compounds critical to cognitive function.

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      Small Intestinal Bacterial Overgrowth (SIBO): What is SIBO, What Causes It, and Can HMO Prebiotics Benefit SIBO?

      August 10, 2022 13 min read

      This article answers the following questions about SIBO: 

      • What Is SIBO?
      • What Are the Symptoms of SIBO? 
      • What Are the Top Risk Factors For SIBO?
      • How to Test and Diagnose SIBO?
      • What Are the Current Treatments For SIBO? 
      • Can HMOs Help With SIBO? 
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      What is Bifidobacteria animalis and Its Effect on Human Health?

      August 10, 2022 9 min read

      Since the discovery of Bifidobacteria in the late 1800’s, it really has grown, not only in the number of strains, but also in popularity. Its benefits to us are plentiful, from our first moments on the planet it becomes an important partner in developing our microbiome and gets busy producing numerous vitamins, and important chemicals as well as aiding in the repair and protection of our health. All of this with the only price tag being, having a good lifestyle and eating the right foods. 
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      Layer Origin Blog for Gut Health and Gut Microbiome

      What is Prevotella copri and What Does This Good Microbe Mean for You?

      August 09, 2022 8 min read

      What is Prevotella copri? Prevotella copri is often found in non-western gut microbiomes, particularly those that consume increased levels of fibr. P. copri may be in the spotlight when it comes to inflammatory diseases but the good health giving properties must also be given the chance to shine. How about succinate? Let's see what exactly Prevotella copri can do to our gut community and our overall health?
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Akkermansia muciniphila Uses Human Milk Oligosaccharides to Thrive in Early Life, According to Research

      August 09, 2022 8 min read

      In this article we are going to look at the association between HMOs and Akkermansia muciniphila,and the benefits of Akkermansia to human gut microbiome and gut health. The article will focus on the findings from a research study by Kostopoulos et al, (2020) to understand how this well-studied anaerobic bacterium interacts with human milk oligosaccharides (HMO’s) and help you understand how and why Akkermansia can utilize HMO as their energy source. 
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Can You Avoid Diabetes By Optimizing Your Gut Microbiota?

      August 07, 2022 8 min read

      Within the more than 40 observational studies conducted in humans to assess the relationship between type 2 diabetes and the microbiome, a few genera popped out as being the most significantly altered in patients with type 2 diabetes relative to healthy controls. Specifically, the following bacteria showed a negative association with type 2 diabetes, meaning that populations of these bacteria were diminished in the diabetic patients: Bifidobacterium, Bacteroides, Faecalibacterium, Akkermansia, Rosburia. Read the article and find out what you can do to reduce the risk of getting diabetes. 

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      Layer Origin Blog for Gut Health and Gut Microbiome

      Aging, Gut Microbiome, and Immunity

      August 07, 2022 6 min read

      The development, regulation, and function of the immune system is now known to be inextricably linked to and dependent upon the presence of microorganisms with the ecosystem of the body. We will cover three primary focuses in this article: the effects of aging on the microbiome and the immune system; the impact of age-related shifts in microbiome structure on the health of the host; prebiotic and probiotic interventions geared towards prevent these age-related declines.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      How Your Body’s Physiology and Metabolism Shape Your Gut Microbiome – Examining an Overlooked Factor

      August 07, 2022 6 min read

      The microbiome is inextricably linked to the functioning of our bodies in both health and disease. A review hot off the press in the prestigious journal Science entitled “The microbiome and gut homeostasis” outlines the parameters that can be used to define dysbiosis and homeostasis when it comes to the microbiome by exploring the role of host physiology and metabolism in microbiota composition. 
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Leaky Gut: the Causes, Treatments, and How HMO Prebiotics Can Help

      July 10, 2022 13 min read

      Leaky gut is a state of increased intestinal permeability, which occurs when the layer of epithelial cells that line the intestine becomes “leaky” and has growing gaps between the cells.

      When the intestinal lining becomes impaired and leaky, toxins, pathogens, and too-big proteins can travel out of the gut into the bloodstream, purportedly causing health issues ranging from acne to arthritis to autoimmune diseases.

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      Layer Origin Blog for Gut Health and Gut Microbiome

      Why You Should Know All About Roseburia Bacteria

      July 09, 2022 8 min read

      Roseburiais a bacterial genus belonging to theFirmicutesphylum, which is known for its prolific butyrate-producing capabilities.

      In the recent PREDICT program, researchers identified a particular strain,Roseburia sp. CAG: 182, to be one of the 15 ‘good’ gut microbes that are associated with good health outcomes.

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      Veillonella: The Gut Bacteria Found in Elite Athletes

      July 05, 2022 7 min read

      The Veillonella genus is an interesting one, and many of its members have only recently been discovered. However, three strains have caught our eye because of their inclusion in the PREDICT 1 list of ‘good’ gut microbes. Each of them has interesting, potential health benefits, linked to insulin sensitivity and polyunsaturated fat levels.

      But could it also be considered a performance-enhancing microbe, beneficial for athletes?

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      Firmicutes: One of the Most Important Bacteria You've Never Heard About

      July 04, 2022 8 min read

      Although the human gut microbiome consists of more than 100 trillion microbes, two main phyla make it up:c andFirmicutes. TheFirmicutes phylum consists of over 200 different genera. In this article we discuss why they are considered to be "good". 
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      Layer Origin Blog for Gut Health and Gut Microbiome

      What is Haemophilus parainfluenzae and is it Actually a Good Gut Microbe?

      July 03, 2022 6 min read

      Haemophilus parainfluenzaeis an excellent example of how research constantly evolves and expands. Previous research has found that although this microbe is a common inhabitant of the mouth and throat, it has also been implicated in the development of bone and joint infections, and potentially promotes gut inflammation. Thus, classifying it as a pathogen.

      However, more recent research from the PREDICT studies has found that H parainfluenzaemay have some health-promoting benefits.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Romboutsia ilealis: How is this Bacteria Linked to Healthy Fats?

      July 02, 2022 8 min read

      There is currently little research available into the beneficial effects of Romboutsia ilealis, but it has been circled as one of the 15 good gut microbes by the PREDICT studies. The researchers state that people who had R. ilealis present in their gut had lower levels of inflammation and increased polyunsaturated fat levels.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      The Interplay Between Pharmaceutical Drugs, the Microbiome, and Cancer

      July 01, 2022 7 min read

      A strong link has been observed between microbiome composition and obesity, autoimmunity, diabetes, and certain cancers, namely colorectal cancer. In the case of colorectal cancer, research implicates the gut microbiome not only in disease severity and rate of progression, but also in treatment efficacy.
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      The Microbiome and Cardiovascular Disease – A 1124 Person Study

      July 01, 2022 5 min read

      A recent study published in the prestigious journal Nature Medicine entitled “Microbiome and metabolome features of the cardiometabolic disease spectrum” characterized the microbiome signatures of healthy individuals, individuals with metabolic dysfunction, and individuals with overt cardiovascular disease. The microbiome signatures across groups are so striking that they may be even more effective clinically useful than the convention risk markers.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Oscillibacter sp. 57_20: What is it and Why Should You Care?

      June 19, 2022 8 min read

      Oscillibacter sp. 57_20 is a member of the Firmicutes family and has been identified as one of the ‘good’ gut bugs in the PREDICT study series. Oscillibacter sp. 57_20 has only recently been discovered, so not much is known about it yet. That means there is a lot of information that scientists are yet to discover, and in the research world, that’s exciting stuff. 
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Gut health before and during pregnancy: shaping future generations

      June 18, 2022 10 min read

      Aside from the dramatic shifts that take place in the maternal gut microbiome during pregnancy, several factors render the gut vulnerable to dysbiosis as a result of poor diet, obesity, and stress. There are, however, positive steps that can be taken to improve gut health and avoid these potentially negative outcomes before and during pregnancy.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Can Oral Health Affect Your Gut Microbiome?

      June 16, 2022 9 min read

      The oral microbiome is just as important to overall health as the gut microbiome. It’s also just as sensitive to changes in diet. Too much sugar can promote bad bacteria. The bacteria in the mouth are similar to those in the gut but tend to thrive in lower diversity. These include Bifidobacteria and Lactobacillus.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Does the Gut Microbiota Hold the Secret to Autism?

      June 15, 2022 6 min read

      We know for a fact that the gut microbiome contributes directly to human development and health. We are also certain that the microbiome can influence intellectual development. We aren’t completely sure how, though. We know certain bacteria produce certain chemicals that act as neurotransmitters and hormones that directly control brain signaling.

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      Improving Gut Health for Kids and Teenagers

      June 12, 2022 8 min read

      Much is made of the methods to improve adult gut health. But what about kids and teenagers? Improving the gut health of younger individuals is equally important. This article discusses ways to achieve that goal.
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      100 Questions About Human Milk Oligosaccharide Prebiotics (HMOs)

      June 07, 2022 22 min read

      HMO stands for human milk oligosaccharides — a type of sugar abundant in human breast milk. This is a straightforward look at the 100 most common questions about Human Milk Oligosaccharides (HMO prebiotics) with brief but detailed answers. The goal is to help you quickly learn more about these fascinating and massively beneficial sugar molecules.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      HMO Prebiotic is a Must if You're Taking Certain Probiotics. New Research Explains Why.

      June 06, 2022 6 min read

      Can a synbiotic consisting of a combination of B. infantis and HMOs lead to the successful engraftment of B. infantis into the microbiome of healthy adults?
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      The Gut-Skin Axis: Why Maintaining Gut Health Should be Part of Your Beauty Routine

      June 06, 2022 8 min read

      Your skin is your body’s biggest organ. It can weigh up to 8 pounds and can cover a surface of 22 square feet. It acts as a highly sensitive sensor, packed with nerves for translating information to the brain from the outside world. It is responsible for one of our most important senses: the sense of touch. In the past decade, so much attention has been given to holistic approaches to health and wellness, with growing interest in gut health. Questions are beginning to emerge regarding a link between the gut and skin.
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      What is Eubacterium eligens and Why Should You Care?

      June 03, 2022 7 min read

      E. eligens is part of the phylum known as Firmicutes. One of the jobs of this group of bacteria is to keep our colon healthy. They help to achieve this by producing butyrate which has numerous health benefits for humans. E. eligens has been identified by the PREDICT 1 study as one of the 15 important good bacteria. This article will look at the importance of E. eligens and how even if it may only be a small part of our gut ecosystem, without it, the puzzles will not be completed.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Microbiome and Mood: How Does Our Gut Affect How We Feel?

      June 03, 2022 8 min read

      The constant communication between our guts and brains plays a role in the development of mental health disorders, including depression, anxiety, stress, and bipolar disorder. Studies on the gut-brain axis — and how to improve the function of both — are ever-growing, hopefully leading to potential clinical implications in the future. This connection is not just for people with poor mental health — probiotics may also maintain or enhance mood and reduce stress in healthy people.  
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      How the Gut Microbiome Affects Weight Management

      June 01, 2022 7 min read

      New scientific research is revealing that the gut microbiome may actually determine whether you even have a chance to lose weight. 

      In this article we’ll explore how the microbiota influences weight loss, particularly in the context of diet and exercise. We’ll look at how the microbiota differs between healthy and obese individuals and discuss ways to shape the gut microbiota that can actually help with weight loss.

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      What is Faecalibacterium Prausnitzii and How Can You Increase Faecalibacterium Prausnitzii?

      May 25, 2022 7 min read

      Faecalibacterium prausnitzii is part of a group of bacteria called Firmicutes and is a common inhabitant of the human gut. Researchers from ZOE have identified F prausnitzii as one of the 15 good gut microbes outlined in their study.

      Because Faecalibacterium prausnitzii is so important for supporting your gut and general health, it is important to eat a healthy and diverse diet as well as make healthy lifestyle choices.

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      Fecal Microbiota Transplants

      May 22, 2022 8 min read

      Microbial transplants are a common practice and are successful at treating, even reversing, a number of diseases and health issues. In this post, we’ll discuss the frontier of fecal microbial transplants – what they are, how they work, and why someone would do this.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      Alzheimer’s Disease – Is the Gut Microbiome the Missing Link?

      May 18, 2022 6 min read

      There is no cure for Alzheimer’s, and we’re only beginning to identify treatments. In this post we’ll explore how Alzheimer’s works. Then we’ll discuss the relationships between the microbiome and the development of diseases like Alzheimer’s, and how these gut bacteria may hold the key to the cure to diseases like Alzheimer’s.
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      Layer Origin Blog for Gut Health and Gut Microbiome

      What Does the World's Largest In-depth Nutritional Research Study Say About the Gut Microbiome?

      May 12, 2022 7 min read

      The PREDICT series of studies, including PREDICT 1, is the largest, in-depth nutritional program in the world. The PREDICT 1 study helped to define links between a person’s diet, gut microbiome, and cardiometabolic health biomarkers from a cohort of 1100 participants. Learn more about how your genes, microbiome, and food interplay with each other and the surprising 15 most important bacteria in your gut.
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      How to Boost Akkermansia in Your Gut? – A Comprehensive Guide

      May 08, 2022 9 min read

      Akkermansia are found in both the adult and infant gut. Interestingly, Akkermansia are present in colostrum and breast milk. Their consumption during infancy seeds the infant gut with these beneficial bugs. The presence of A. muciniphila in the adult gut is associated with lower rates of cardiovascular disease and protection against type 2 diabetes, obesity, and chronic, low grade inflammation. 
      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      What Are Short Chain Fatty Acids and Why Are SCFAs Important to Your Gut Health?

      May 04, 2022 8 min read

      Short-chain fatty acids are made in the gut by the friendly bacteria that reside there. Your body isn’t equipped with the enzymes needed to digest dietary fibre, so your gut bacteria do it for you.

      In this article, we explore the SCFAS and their benefits. 

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      How to Support Your Gut Health During Travel

      April 30, 2022 6 min read

      Given the impact travel can have on the gut microbiome, focusing on practices to support gut health when traveling is important.

      Consuming foods that can have a beneficial impact on gut health, being mindful of staying hydrated, and remaining cautious of food safety risks are all key steps you can take to care for your gut during travel. 

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      Layer Origin PureHMO® Product Guide

      April 30, 2022 2 min read

      A shortcut for figuring out which Layer Origin Nutrition product is best for your gut health goals. 

      PureHMO® Super Prebiotic Powder? PureHMO® capsules? Organic Apple Peel Powder? 

      Every product and the benefits are explained here. 

      Read More
      Layer Origin Blog for Gut Health and Gut Microbiome

      April is Irritable Bowel Syndrome Awareness Month: Here’s What You Need to Know About IBS

      April 24, 2022 7 min read

      April is irritable bowel syndrome awareness month and has been since 1997 when the International Foundation for Gastrointestinal Disorders declared it so.

      But what exactly does it mean?

      Well, during the month of April more attention is given to the condition that affects approximately 11% of the world’s population[i]. In this article, we explore what IBS is, what causes it, how it can be treated, and of course, the link between IBS and the gut microbiome.

      Read More
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