GUT HEALTH KNOWLEDGE CENTER

A new 2025 study suggests that gluten and wheat may not be the main cause of symptoms for many people with IBS. Discover what researchers found, why expectations and food...

Your gut doesn’t just digest food—it plays a crucial role in how you feel, your metabolism, immune function, energy levels, and so much more. But beyond popping a probiotic, how...

Think your Bifidobacteria populations might be low? Keep reading to discover the 7 signs that could suggest you’re right.  Content outline What are Bifidobacteria? 7 possible signs that you have...

Short-chain fatty acids connect your diet, gut microbiome, and immune system. This article explains how they are produced, how they may support the gut barrier and infection defenses, and how...

New research suggests intestinal dendritic cells may play an important role in helping the brain adapt after gut microbial colonization. Learn how immune signaling, the gut-brain axis, and the microbiome...

Not all Akkermansia supplements are the same. Discover the differences between live probiotics and pasteurized postbiotics, explore the latest scientific evidence, and find out why dual-formulation supplements are generating growing...

Weight regain after successful weight loss is common, but emerging research suggests that the gut bacterium Akkermansia muciniphila may help slow the process. This article explores the latest clinical evidence...

Compare Layer Origin’s top HMO prebiotics and probiotics. Find the perfect fit for your gut health goals, from PureHMO to Akkermansia and SuperHMO prebiotics.

This article explores whether your body can produce Urolithin A, a compound linked to healthy aging, from foods rich in ellagic acid. It explains the role of the gut microbiome,...

New research examining more than 800 children reveals that diet may play a stronger role in shaping the gut microbiome in autism than previously understood. The study links lower diet...

The low FODMAP diet is widely used to manage IBS symptoms, but it may come with unintended consequences, including reduced gut microbiome diversity and nutrient deficiencies. This article explores the...

Discover how Bifidobacterium infantis YLGB-1496 supports toddler gut health, immunity, and respiratory protection in a 12-week clinical study.

New research shows that gut microbes help regulate cholesterol metabolism through their influence on bile acids. Scientists discovered a new molecule produced through interactions between gut bacteria and intestinal cells...

Nonalcoholic steatohepatitis (NASH) is a progressive liver disease with limited treatment options and a growing global burden. Emerging research suggests the gut microbiome plays a critical role in disease development...

When it comes to aging, your gut might not be top of your list of organs that can help you grow old healthily, but emerging research suggests it should be....

Discover the benefits behind the Japanese eating principle of 'Hara Hachi Bu', what it means, how to incorporate it into your daily diet, and how it can benefit health.

The human milk microbiome contains beneficial bacteria such as Bifidobacterium longum that help shape the infant gut during the first six months of life. A new metagenomic study of 507...

A novel synbiotic formulation combining human milk oligosaccharides, ellagic acid and probiotics may help support healthy aging by enhancing urolithin A production and promoting mitochondrial health. Early experimental findings suggest...

If you’ve ever noticed mood changes, bloating, fatigue, headaches, or anxiety in the days leading up to your period, you’re not alone—but your gut probably isn’t the first place you’d...

Discover whether a mother's diet alone can affect her offspring's gut microbiome composition and future health. Here, we explore the results of a recent study in animals that shows that...

The gut microbiome is emerging as a powerful player in cancer care. From shaping immunotherapy response to influencing chemotherapy side effects, microbial communities help determine how treatments perform. This article...

A global study analysing over 11,000 gut microbiomes has uncovered a previously unknown bacterium linked to better health. Discover what CAG-170 is, why it matters, and how it could shape...

Clostridium difficile, commonly known as C. diff, is a bacterium that can cause severe diarrhea and other intestinal problems. The bacterium can be found in the gut of healthy individuals,...

Maintaining muscle strength becomes more challenging with age, illness, or conditions like GNE myopathy. A new clinical trial shows that 6′-Sialyllactose (6′-SL) — a naturally occurring human milk oligosaccharide —...

New research shows that human milk oligosaccharides (HMOs) can directly inhibit and kill Streptococcus pneumoniae, a leading cause of serious infections in infants. The findings highlight HMOs potential role in...

Discover the science-backed health benefits of fermented foods like kefir, kimchi, sauerkraut, and kombucha in this guide. Learn how these gut-friendly staples can support digestion, reduce inflammation, boost immunity, enhance...

Discover how human milk oligosaccharides (HMOs) like 2′-FL and LNnT may benefit not just infants, but adults too. This article explores a groundbreaking clinical study showing that these unique sugars...

Non-caloric artificial sweeteners like aspartame, saccharin, and sorbitol are considered to be guilt-free, healthier alternatives to natural sugar. However, emerging research questions these claims, particularly as animal research suggests they...

Have you ever had trouble sleeping? Maybe you thought it was because you were stressed or because of too many late nights. And they could be contributing factors, but your...

Most of colostrum's health benefits stem from its protein compounds: lactoferrin, antibodies, and growth factors. However, cow colostrum contains zero prebiotic fibers. In comparison, human colostrum contains a significant amount of...

This article is packed with everything you need to know about inflammatory bowel disease, from what it is, what causes it, how it manifests, to how it's treated and what...

Discover how FUT2 gene variants define non-secretor status, influence microbiome composition and immune responses, and how HMOs such as 2’-FL can help recreate a more secretor-like gut environment.

Die-off symptoms can occur when the gut microbiome shifts quickly—often after adding prebiotics, probiotics, or making big dietary changes. This article explains what die-off is, why it happens, and how...

Learn how to pair 2'-FL HMOs with Bifidobacteria for maximum gut health. Discover if you need to 'seed' or 'feed' your microbiome based on 3 specific gut scenarios. Read the...

A new clinical study reveals that 2′-fucosyllactose (2′-FL), a human milk oligosaccharide, can reshape the gut microbiome, influence key metabolic hormones, and even enhance aspects of cognitive performance in older...

Learn the essentials of gut inflammation: what causes it, the common symptoms like brain fog and bloating, and how to reduce it naturally through diet, lifestyle, and HMO supplements