GUT HEALTH KNOWLEDGE CENTER

3'-sialyllactose is the most abundant sialylated human milk oligosaccharide in human milk and has pivotal roles in the developing human gut microbiome. Recent research has also shed light on how this HMO could also have a critical role in bone health, even offering some hope for a new future osteoporosis therapy.

In this article, we explore 9 ways you can help promote the effectiveness of probiotics to help them become permanent residents in your gut.

Bloating is one of the most commonly reported digestive complaints. Here we examine some of the evidence that suggests human milk oligosaccharides could provide some much needed relief.

Find out how HMOs can enhance the adherence of Bifidobacteria to the intestinal epithelial cells, promoting the colonization of these health-promoting probiotics.

The gut, also known as the second brain, has a direct hotline to the brain called the gut-brain axis. This unique bi-directional communication pathway links the gut microbiota with the central nervous system (CNS) and can directly influence brain function and health. Secondary to this, human milk oligosaccharides (HMOs) are important prebiotics that can modulate the composition of the gut microbiome which could influence the activity and function of the brain. Here we investigate how.

Join us as we examine the results of a study revealing that a combination of synbiotics and dietary fiber can induce significant weight loss, comparable to GLP-1 weight loss injections, like Ozempic.

Discover the results from our recent consumer survey to find out the real-life benefits of human milk oligosaccharides (HMOs) for health.

We all know we should eat more fiber but what if our gut doesn't react to fiber in the way we think it should? In this article, we delve into the results of a recent study that identifies the individual responses to resistant starch.

Discover how HMOs may relieve or improve gastrointestinal symptoms in autistic children.

Here, we explore the results of recent research investigating the potential effects of HMOs (2'-FL, LNnT, 3'-SL, 6'-SL) at daily doses of 0.3 - 5 g/day.

Get ready to learn about the crosstalk between the gut microbiota and the intestinal mucosal immunity has been identified as a contributing factor for IBS.

Aging is inevitable, but why do some people age better than others? The answer lies in a mix of genetic, environmental, and lifestyle factors. Another key player is the gut microbiome, which might hold the key to longevity and health. Using a review by Ghosh et al. (2022), we explore the role of the gut microbiome in healthy aging, chronic disease development, and strategies to help you age healthily. 

Human milk oligosaccharides (HMOs), particularly the glycan known as 2’-Fucosyllactose (2’-FL), have been a cornerstone in neonatal nutrition, offering the first sweet taste and vital energy while establishing a thriving gut microbiome. Recent studies have expanded the understanding of these substances, with research showing 2’-FL's pivotal role in not only fostering beneficial gut bacteria but also in potentially mitigating adult conditions such as colitis. The Schalich et al. (2024) study further explores this by investigating 2’-FL's ability to modulate gut microbial metabolism, suggesting a promising future for HMOs in adult disease prevention and therapy, particularly for inflammatory bowel diseases like colitis.

Discover some of the unique mechanisms Akkermansia employs to survive in the human gut and the genetics behind how this fascinating bacterium can maintain cholesterol homeostasis.

Understand how cranberry extracts could improve the composition of the gut microbiome, increasing the abundance and activities of friendly bacteria and potentially offering a solution to combat the effects of the Western diet.

Aging is a fact of life, even if we don't like to admit it. In this article, we'll delve into 4 of the tell-tale signs of aging to help us better understand the process and explore if it can be reversed.

The human gut microbiome is a myriad of microbes working together in harmony, but it's also the hub of numerous biological transactions. The conversion of the polyphenols, ellagic acid and ellagitannins, into urolithin A is an interesting and hot topic. Urolithin A has been earmarked for its anti-aging potential, and in this article, we explore its benefits for bone, muscle, and brain health.

Take a look at a consumer's gut microbiome data before and after taking PureHMO, and see what beneficial bacteria have been boosted by PureHMO.

In the vast ecosystem of the human gut, Akkermansia muciniphila is emerging as a pivotal player and taking center stage as a next-generation probiotic. It's unique interactions with the human gut not only bolster its own population but also promote synergies with other beneficial gut bacteria, leading to a more resilient and healthy microbiome. Understanding the intricate and complex interplay between dietary fibers, host-derived substances, other probiotic bacteria and Akkermansia muciniphila, offers new opportunities in nurturing the human gut and optimizing wellbeing.

Scientists have recently found that certain gut microbes may have protective benefits against cardiovascular disease. One particular genus, Oscillibacter, is equipped with the tools needed to metabolize cholesterol in its surrounding environment, helping to rid it from the body.

Discover eight effective ways to fine-tune your gut health for enhanced metabolism and weight management in our latest blog. From incorporating prebiotics and probiotics to exploring exercise, learn how simple dietary and lifestyle changes can lead to significant health benefits.

The study by Li et al., (2024) assessed if resistant starch as a dietary supplement could affect participants with excess weight. Earlier research has shown that resistant starch, a type of fermentable fibre that cannot be digested by humans and is instead, fermented by members of the gut microbiota, can reduce total body fat in mice. 

Discover the benefits of the new Akkermansia product from Layer Origin Nutrition. Packed with a next-generation probiotic, a human milk oligosaccharide, and resistant starch, this formula supports both general and gut health, and targets your metabolism.

In the human body, oxidants are generated from metabolic processes that can cause oxidative reactions. These are the bad. But the good, anti-oxidants work hard to rid these reactive molecules from the body to prevent the ugly, oxidative stress, from taking hold. Here, we'll walk you through what each one of these means for your health and what you can do to lower the risk of oxidative stress and chronic disease.

Discover the difference between fibre, prebiotics or prebiotic fibre and how they each benefit your health.

Discover the hidden wonders of apple peel as we reveal the health benefits of quercetin and other nutrients found within. Learn how incorporating the whole apple into your diet can enhance wellness and promote better health.

Find out why combining prebiotics and probiotics together can have a synergistic benefit on your gut health. Read on to get a comprehensive guide to synbiotics.

The holiday season is full of fun and festivities. But these activities can leave your gut vulnerable. In this article, we explore six things you can do to support your intestinal ecosystem after the holidays.