June 09, 2023 3 min read
Saccharomyces boulardii, commonly known as the "magic yeast," is a probiotic yeast strain that has been extensively studied for its beneficial effects on gut health. This unique yeast strain is not a part of the normal gut microbiota, but it has been found to colonize the gut and exert several positive effects on the host. In this response, we will provide an overview of Saccharomyces boulardii, its potential health benefits, and the scientific evidence supporting its use.
Overview:
Potential Health Benefits:
Scientific Evidence:
In summary, Saccharomyces boulardii is a unique probiotic yeast strain that has been found to have several potential health benefits, particularly for digestive health. The scientific evidence supporting its use is robust, and it is considered safe and well-tolerated for most people.
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References:
McFarland LV. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol. 2010;16(18):2202-2222. doi: 10.3748/wjg.v16.i18.2202
Dinleyici EC, Eren M, Ozen M, Yargic ZA, Vandenplas Y. Effectiveness and safety of Saccharomyces boulardii for acute infectious diarrhea. Expert Opin Biol Ther. 2012;12(4):395-410. doi: 10.1517/14712598.2012.668013
McFarland LV. Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections. Anaerobe. 2009;15(6):274-280. doi: 10.1016/j.anaerobe.2009.09.002
McFarland LV. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol. 2010;16(18):2202-2222. doi: 10.3748/wjg.v16.i18.2202
Kabbani TA, Pallav K, Dowd SE, et al. Prospective randomized controlled study on the effects of Saccharomyces boulardii CNCM I-745 and amoxicillin-clavulanate or the combination on the gut microbiota of healthy volunteers. Gut Microbes. 2017;8(1):17-32. doi: 10.1080/19490976.2016.1267896
Dinleyici EC, Eren M, Ozen M, Yargic ZA, Vandenplas Y. Saccharomyces boulardii for prevention of necrotizing enterocolitis in preterm infants: a randomized, controlled study. Acta Paediatr. 2013;102(12):e560-e565. doi: 10.1111/apa.12414
McFarland LV. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol. 2010;16(18):2202-2222. doi: 10.3748/wjg.v16.i18.2202
Ihekweazu FD, Versalovic J. Development of the Pediatric Gut Microbiome: Impact on Health and Disease. Am J Med Sci. 2018;356(5):413-423. doi: 10.1016/j.amjms.2018.06.011
Wohlgemuth S, Haller D, Blaut M, Loh G. Reduced microbial diversity and high numbers of one single Escherichia coli strain in the intestine of colitic mice. Environ Microbiol. 2009;11(6):1562-1571. doi: 10.1111/j.1462-2920.2009.01893.x
Zhou X, Brown CJ, Abdo Z, Davis CC, Hansmann MA, Joyce P, Foster JA, Forney LJ. Differences in the composition of vaginal microbial communities found in healthy Caucasian and black women. ISME J. 2007 Aug;1(2):121-33. doi: 10.1038/ismej.2007.12. PMID: 18043614.
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