What is Roseburia?

May 25, 2023 2 min read

What is Roseburia?

Roseburia is a genus of bacteria belonging to the family Lachnospiraceae, which is known for its beneficial effects on gut health. Here are some key points about Roseburia:

  • Roseburia is a Gram-positive, anaerobic, butyrate-producing bacteria that is commonly found in the human gut. It is one of the most abundant species of bacteria in the human colon, where it plays a crucial role in maintaining gut health.
  • Roseburia is known to have a positive impact on the immune system by producing short-chain fatty acids (SCFAs) such as butyrate, which serve as a source of energy for colon cells and are involved in regulating inflammation in the gut. Butyrate also has anti-inflammatory properties and is important for the maintenance of gut barrier function.
  • Studies have shown that a reduction in Roseburia abundance in the gut is associated with several inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis. In addition, a decrease in Roseburia levels has been observed in individuals with obesity and type 2 diabetes.
  • Roseburia is also important for the breakdown of complex carbohydrates, such as dietary fiber, which cannot be digested by the human host. The bacteria uses enzymes to break down these complex carbohydrates into simple sugars, which can then be used for energy production by the host. This process is important for maintaining a healthy gut microbiome.
  • Furthermore, Roseburia has been shown to produce metabolites that have potential therapeutic effects, such as bacteriocins, which are antimicrobial peptides that can help to prevent the growth of harmful bacteria in the gut.

References:

  1. Belenguer A, Duncan SH, Calder AG, Holtrop G, Louis P, Lobley GE, Flint HJ. Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut. Appl Environ Microbiol. 2006 Dec;72(12):3593-9. doi: 10.1128/AEM.72.5.3593-3599.2006. PMID: 16751530; PMCID: PMC1489366.
  2. Lopez-Siles M, Enrich-Capó N, Aldeguer X, Sabat-Mir M, Duncan SH, Garcia-Gil LJ, Martinez-Medina M. Alterations in the Abundance and Co-occurrence of Akkermansia muciniphila and Faecalibacterium prausnitzii in the Colonic Mucosa of Inflammatory Bowel Disease Subjects. Front Cell Infect Microbiol. 2018 Mar 13;8:281. doi: 10.3389/fcimb.2018.00281. PMID: 29594161; PMCID: PMC5853734.
  3. Louis P, Flint HJ. Formation of propionate and butyrate by the human colonic microbiota. Environ Microbiol. 2017 Jan;19(1):29-41. doi: 10.1111/1462-2920.13589. Epub 2016 Dec 20. PMID: 27813210.
  4. Vital M, Howe AC, Tiedje JM. Revealing the bacterial butyrate synthesis pathways by analyzing (meta)genomic data. MBio. 2014 Dec 9;5(6):e00889. doi: 10.1128/mBio.00889-14. PMID: 25491348; PMCID: PMC4278896.
  5. Rossi M, Amaretti A, Raimondi S. Folate Production by Probiotic Bacteria. Nutrients. 2011;3(1):118-134. doi:10.3390/nu3010118


Leave a comment


Also in THE LAYER ORIGIN NUTRITION BLOG

Do HMOs inhibit Candida Invasions?
Do HMOs inhibit Candida Invasions?

May 28, 2023 7 min read

Candida albicans is a common commensal inhabitant on and within the human body. Most of the time it causes us no harm, but in the right conditions it can thrive leading to infection. Some groups are particularly vulnerable to C. albicans invasion, like premature infants. In this article, we analyse a study by Gonia et al (2015) to find out if HMOs can protect premature infants from the nasty effects of C. albicans invasion.
Read More
What is Streptococcus thermophilus?
What is Streptococcus thermophilus?

May 26, 2023 2 min read

Streptococcus thermophilus is a lactic acid bacteria that is widely used in the food industry as a starter culture in the production of various dairy products such as yogurt and cheese. It is a gram-positive, non-motile, and non-sporulating bacterium that can grow under aerobic and anaerobic conditions. This article discusses key points about Streptococcus thermophilus and its benefits!
Read More
What is Faecalibacterium prausnitzii?
What is Faecalibacterium prausnitzii?

May 24, 2023 2 min read

In this article, we discuss Faecalibacterium prausnitzii, which is a Gram-positive, anaerobic, commensal bacterium that belongs to the Firmicutes phylum. It is considered to be a beneficial bacterium for human health due to its various functions and benefits. In the full article, you'll find info on the different strains and their benefits!
Read More