What is leaky gut syndrome?

July 05, 2023 2 min read

What is leaky gut syndrome?

"Leaky gut syndrome," also known as increased intestinal permeability, is a condition in which the lining of the intestine becomes more porous, allowing toxins, bacteria, and other substances to pass into the bloodstream. The concept of leaky gut syndrome is controversial, and some experts argue that it is not a recognized medical condition. However, there is some evidence to suggest that increased intestinal permeability may be associated with certain health conditions.

Some potential causes of increased intestinal permeability include:

  • chronic stress,
  • poor diet,
  • overuse of antibiotics,
  • certain medications (such as nonsteroidal anti-inflammatory drugs).

Research has shown that certain conditions, such as inflammatory bowel disease, celiac disease, and type 1 diabetes, are associated with increased intestinal permeability (1).

Symptoms of leaky gut syndrome may include bloating, gas, cramps, fatigue, joint pain, skin rashes, and food sensitivities. However, these symptoms are non-specific and can be caused by a wide range of conditions.

There is some preliminary evidence to suggest that certain dietary and lifestyle changes may help to improve intestinal permeability. For example, reducing intake of inflammatory foods (such as sugar and processed foods), increasing intake of fiber and prebiotics, and taking probiotics may help to promote a healthy gut microbiome and reduce inflammation in the gut (2).

However, more research is needed to fully understand the relationship between increased intestinal permeability and overall health, as well as the most effective treatments for this condition.

 

References:

Fasano, A. (2012). Leaky gut and autoimmune diseases. Clinical reviews in allergy & immunology, 42(1), 71-78.

Zmora, N., Zilberman-Schapira, G., & Segal, E. (2019). The gut microbiome and its potential therapeutic application. Nature Reviews Gastroenterology & Hepatology, 16(6), 332-343.


Leave a comment


Also in GUT HEALTH KNOWLEDGE CENTER

How Can the Gut Microbiome Help Reverse Aging
How Can the Gut Microbiome Help Reverse Aging?

June 09, 2024 8 min read

Aging is a fact of life, even if we don't like to admit it. In this article, we'll delve into 4 of the tell-tale signs of aging to help us better understand the process and explore if it can be reversed.
Read More
New Study Links Gut Microbiome Composition With Your Social Decision-Making
New Study Links Gut Microbiome Composition With Your Social Decision-Making

June 01, 2024 7 min read

Read More
Layer Orignin - The Health Benefits of Urolithin A - A Postbiotic Produced In Your Gut - for Bone, Muscle, Brain Health, and Aging
The Health Benefits of Urolithin A - A Postbiotic Produced In Your Gut - for Bone, Muscle, Brain Health, and Aging

May 19, 2024 7 min read

The human gut microbiome is a myriad of microbes working together in harmony, but it's also the hub of numerous biological transactions. The conversion of the polyphenols, ellagic acid and ellagitannins, into urolithin A is an interesting and hot topic. Urolithin A has been earmarked for its anti-aging potential, and in this article, we explore its benefits for bone, muscle, and brain health.
Read More