September 29, 2023 4 min read
There is a growing body of research suggesting that prebiotic supplements may have a positive impact on mental health, particularly in the area of mood regulation and stress management.
Here are some potential ways in which prebiotic supplements may improve mental health:
References:
Cryan JF, O’Riordan KJ, Cowan CSM, et al. The Microbiota-Gut-Brain Axis. Physiol Rev. 2019;99(4):1877-2013. doi: 10.1152/physrev.00018.2018
Burokas A, Moloney RD, Dinan TG, Cryan JF. Microbiota regulation of the mammalian gut-brain axis. Adv Appl Microbiol. 2015;91:1-62. doi: 10.1016/bs.aambs.2015.02.001
Dash S, Clarke G, Berk M, Jacka FN. The gut microbiome and diet in psychiatry: focus on depression. Curr Opin Psychiatry. 2015;28(1):1-6. doi: 10.1097/YCO.0000000000000117
Schmidt K, Cowen PJ, Harmer CJ, Tzortzis G, Errington S, Burnet PW. Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers. Psychopharmacology (Berl). 2015;232(10):1793-801. doi: 10.1007/s00213-014-3810-0
Holscher HD. Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes. 2017;8(2):172-184. doi: 10.1080/19490976.2017.1290756
Liu RT, Walsh RFL, Sheehan AE. Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials. Neurosci Biobehav Rev. 2019;102:13-23. doi: 10.1016/j.neubiorev.2019.04.013
Mohammadi AA, Jazayeri S, Khosravi-Darani K, et al. The effects of probiotics on mental health and hypothalamic-pituitary-adrenal axis: A randomized, double-blind, placebo-controlled trial in petrochemical workers. Nutr Neurosci. 2016;19(9):387-395. doi: 10.1179/1476830515Y.0000000048
Reis DJ, Ilardi SS. Effects of a probiotic supplement on depression and mild cognitive impairment: A randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2018;79(5):17m11880. doi: 10.4088/JCP.17m11880
De Palma G, Collins SM, Bercik P, Verdu EF. The microbiota-gut-brain axis in functional gastrointestinal disorders. Gut Microbes. 2014;5(3):419-429. doi: 10.4161/gmic.29205
Dinan TG, Stanton C, Cryan JF. Psychobiotics: A novel class of psychotropic. Biol Psychiatry. 2013;74(10):720-726. doi: 10.1016/j.biopsych.2013.05.001
Shariatpanahi SP, Shariatpanahi P, Shahbazi Y. A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome. Gut Pathog. 2009;1(1):6
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