May 16, 2023 2 min read
Yes, prebiotic supplements can be taken long-term.
Overall, prebiotic supplements, including HMO prebiotics, can be taken long-term if deemed safe and well-tolerated by the individual.
References:
Bindels, L. B., Segura Munoz, R. R., Gomes-Neto, J. C., Mutemberezi, V., Martinez, I., Salazar, N., ... & Walter, J. (2021). Resistant starch can improve insulin sensitivity independently of the gut microbiota. Microbiome, 9(1), 1-16.
Holscher, H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut microbes, 8(2), 172-184.
Holscher, H. D. (2020). Dietary fiber and prebiotics and the gastrointestinal microbiota. In Bioactive Components of Human Milk (pp. 455-473). Academic Press.
Hutkins, R. W., Krumbeck, J. A., Bindels, L. B., Cani, P. D., Fahey Jr, G., Goh, Y. J., ... & Versalovic, J. (2016). Prebiotics: why definitions matter. Current opinion in biotechnology, 37, 1-7.
Kellow, N. J., & Coughlan, M. T. (2015). Effect of diet-derived non-digestible carbohydrates on the host immune system. Nutrients, 7(10), 7999-8019.
Kumar, M., Nagpal, R., Kumar, R., Hemalatha, R., Verma, V., Kumar, A., ... & Singh, B. (2012). Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. Experimental diabetes research, 2012.
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