PureHMO® Human Milk Oligosaccharide Super Prebiotic Capsules

PureHMO® super prebiotic is a fermented high-purity human milk oligosaccharide with multiple health benefits, originally found in mother's milk. This super prebiotic offers more benefits than traditional oligosaccharides like GOS, FOS, and inulin due to its specific structure and unique functionality:

  • Promote Digestive Health: supports the growth of 180 Billion CFU probiotics per serving, e.g. Bifidobacterium and Akkermansia Muciniphila, and promotes a healthy gut environment. 
  • Support Immune Functions: HMOs are more effective than non-human prebiotics in stimulating the body's natural immune system, blocking pathogens and viruses, and reducing inflammation.
  • Improve Cognitive Function: Unlike other prebiotic and probiotic products for adults, HMO metabolites promote brain development, neuronal transmission, and cognition.


      Super Prebiotic Fiber

      Feed Bifidobacteria and Akkermansia, increase beneficial bacteria in gut, build a healthy gut ecosystem.

      Cognitive Support

      HMO provide nutrients for brain development and cognitive functions

      Gut Comfort

      Clinically proven to reduce gas, bloating, constipation, and stomach pain, and other IBS symptoms

      Healthy Metabolism

      Boost the number of slim probiotics in the gut, which help with food digestion and improve metabolism

      How It Works

      Experts' Opinion On HMO

      expert opinion review stars


      "HMOs are helping to steer the gut towards immunity and steering the macrophages towards restoration of the gut lining — I actually know a lot of functional medicine doctors using this with their patients now."

      Host, The Ben greenfield fitness podcast

      expert opinion review stars

      Dr. William Davis, MD

      "HMOs also result in marked increases in intestinal butyrate that nourishes and heals the intestinal lining and yields metabolic benefits such as reduced blood sugar, reduced insulin resistance, reduced blood pressure, and improved mood, mental health, and sleep."

      Author of NY Times Best Seller, Wheat Belly

      expert opinion review stars

      DR. RHONDA , Ph.D.

      "These beneficial bacteria produce short-chain fatty acids that prevent colonization of pathogenic bacteria in the gut. This bacteria (good bacteria promoted by HMOs) has been shown to set up the immune system."


      expert opinion review stars


      "They are food for developing gut microbiome. They are prebiotics and they actually help the right bacteria, specifically bifidobacteria, to grow. And this also helps with development of the immune system."



      No. Our HMO is technically something referred to as HiMO, which stands for Human identical Milk Oligosaccharide. It is produced via a complex fermentation and precise purification process and results in a powder that is molecularly identical to the HMO that is in human milk. All the benefits without any human milk involved.

      Yes. Research has shown that many people with lactose intolerance can tolerate up to 12 grams of lactose in one sitting, which is approximately the amount in one cup (230 ml) of milk. Layer Origin Nutrition recommends a total HMO serving size of 2.0 grams — therefore — even people with with lactose intolerance should be well below the limit of what they can tolerate, if they follow the recommended dosage.

      Believe it or not, it doesn't make a difference either way. This is because the HMO will not be digested the way that food would be digested. HMO makes its way undigested through your body down to the lower intestines, where it becomes the food for probiotic bacteria. So take HMO with food or without food. Either way is fine!

      Customer Reviews

      Based on 57 reviews
      Constance Burns
      Great product

      Has really helped my husband and myself with some minor issues. I would totally recommend this product. These guys are very reasonably priced and the auto ship is very convenient.

      Brittany Hopper
      Really loved this for bloating and digestion

      I started this protocol because I have a really hard time consuming carbs without feeling super bloated and terrible. I truly don't have many issues now with that so thats great.

      Better gut

      Hi I’ve been taking one a day after I did a cleanse of the bad bacteria and feeling so much better! I can digest food much easier.

      Energy boost

      I’ve been using this HMO for just 3 days along with apple peel powder protocol, and I am stunned by the increase in my energy. No nodding off mid-afternoon. Impressive.

      Great quality

      I’ve been using this HMO for over a year. It can be hard to find a good quality product with just 2’FL. This is perfect. Works great. I’m also a certified Immune Centric Health Coach, and I recommend this product as a part of the Apple peels protocol.