Science Reading: Lactoferrin—a multifunctional protein with antimicrobial properties


Lactoferrin is a member of the transferrin family of iron-binding proteins. Numerous functions have been reported and continue to be reported for the protein, some of which are related to its iron-binding properties. Its extensive antimicrobial activities were originally attributed to its ability to sequester essential iron, however, it is now established that it possesses bactericidal activities as a result of direct interaction between the protein or lactoferrin-derived peptides. The following article reviews the antimicrobial activities of lactoferrin and discusses the potential mode of action of lactoferrin-derived cationic peptides against Gram-negative bacteria in the light of recent studies.

Source: Farnaud, Sebastien, and Robert W. Evans. "Lactoferrin—a multifunctional protein with antimicrobial properties." Molecular immunology 40.7 (2003): 395-405.

    Leave a comment

    All blog comments are checked prior to publishing
    The cookie settings on this website are set to 'allow all cookies' to give you the very best experience. Please click Accept Cookies to continue to use the site.
    You have successfully subscribed! Please use code "15LayerOrigin" at checkout to redeem your discount
    This email has been registered